Lamivir HBV
Lamivir HBV contains Lamivudine, an antiviral nucleoside analogue. It is specifically formulated at a lower strength (100 mg) to treat chronic hepatitis B. It works by inhibiting the HBV viral polymerase, which blocks the replication of the hepatitis B virus, reducing the viral load in the body and limiting liver damage.
Dosage by Body Weight
The standard adult dosage is 100 mg once daily, taken with or without food. It is crucial to take this medication regularly at the same time each day. Do not discontinue treatment abruptly, as this can cause a severe worsening of hepatitis B. Regular monitoring of liver function and viral load is required.
- Body Weight
- Below 5 kg
- Dose
- Not routine / safety not established
- Frequency
- Use only if explicitly prescribed
- Tracking Notes
- Safety and efficacy in pediatric patients under 2 years of age have not been fully established.
- Body Weight
- 5-7 kg
- Dose
- 15 mg to 21 mg (using oral solution)
- Frequency
- Once daily
- Tracking Notes
- Pediatric dosing is typically calculated at 3 mg/kg once daily. Use oral solution for accurate dosing.
- Body Weight
- 8-10 kg
- Dose
- 24 mg to 30 mg
- Frequency
- Once daily
- Tracking Notes
- Monitor renal function and liver enzymes regularly.
- Body Weight
- 11-15 kg
- Dose
- 33 mg to 45 mg
- Frequency
- Once daily
- Tracking Notes
- Ensure exact measurement using a calibrated oral dosing syringe.
- Body Weight
- 16-20 kg
- Dose
- 48 mg to 60 mg
- Frequency
- Once daily
- Tracking Notes
- Do not exceed the maximum daily adult dose of 100 mg.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine / safety not established | Use only if explicitly prescribed | Safety and efficacy in pediatric patients under 2 years of age have not been fully established. |
| 5-7 kg | 15 mg to 21 mg (using oral solution) | Once daily | Pediatric dosing is typically calculated at 3 mg/kg once daily. Use oral solution for accurate dosing. |
| 8-10 kg | 24 mg to 30 mg | Once daily | Monitor renal function and liver enzymes regularly. |
| 11-15 kg | 33 mg to 45 mg | Once daily | Ensure exact measurement using a calibrated oral dosing syringe. |
| 16-20 kg | 48 mg to 60 mg | Once daily | Do not exceed the maximum daily adult dose of 100 mg. |
Formulation
Purpose
Treatment of chronic hepatitis B virus (HBV) infection with evidence of hepatitis B viral replication and active liver inflammation.
Generic Name
LamivudineScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.