Hectorol
Hectorol (doxercalciferol) is a synthetic vitamin D2 analog. It undergoes metabolic activation in the body to form 1,25-dihydroxyvitamin D2, an active hormone that helps regulate calcium and phosphorus metabolism, thereby reducing elevated parathyroid hormone (PTH) levels associated with chronic kidney disease.
Dosage by Body Weight
Dosage must be highly individualized based on serum calcium, phosphorus, and intact parathyroid hormone (iPTH) levels. For adult patients on dialysis, the typical starting dose is 10 mcg orally three times weekly (every other day) or 4 mcg intravenously three times weekly. For adult patients with Stage 3 or 4 CKD, the starting dose is 1 mcg orally daily.
- Body Weight
- Below 5 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Safety and effectiveness in pediatric patients have not been established. Use strictly under pediatric nephrologist supervision.
- Body Weight
- 5-7 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Safety and effectiveness in pediatric patients have not been established. Use strictly under pediatric nephrologist supervision.
- Body Weight
- 8-10 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Safety and effectiveness in pediatric patients have not been established. Use strictly under pediatric nephrologist supervision.
- Body Weight
- 11-15 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Dosing in pediatric patients is not standard and requires specialist calculation based on body surface area or clinical parameters.
- Body Weight
- 16-20 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Dosing in pediatric patients is not standard and requires specialist calculation based on body surface area or clinical parameters.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine | Use only if prescribed | Safety and effectiveness in pediatric patients have not been established. Use strictly under pediatric nephrologist supervision. |
| 5-7 kg | Not routine | Use only if prescribed | Safety and effectiveness in pediatric patients have not been established. Use strictly under pediatric nephrologist supervision. |
| 8-10 kg | Not routine | Use only if prescribed | Safety and effectiveness in pediatric patients have not been established. Use strictly under pediatric nephrologist supervision. |
| 11-15 kg | Not routine | Use only if prescribed | Dosing in pediatric patients is not standard and requires specialist calculation based on body surface area or clinical parameters. |
| 16-20 kg | Not routine | Use only if prescribed | Dosing in pediatric patients is not standard and requires specialist calculation based on body surface area or clinical parameters. |
Formulation
Purpose
Treatment of secondary hyperparathyroidism in patients with chronic kidney disease (CKD) on dialysis, and patients with Stage 3 or Stage 4 CKD.
Generic Name
DoxercalciferolScheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.