Glumetza
Glumetza is an extended-release formulation of metformin hydrochloride, an oral biguanide antihyperglycemic agent. It works by decreasing hepatic glucose production, decreasing intestinal absorption of glucose, and improving insulin sensitivity.
Dosage by Body Weight
The recommended starting dose of Glumetza is 500 mg or 1000 mg taken orally once daily with the evening meal. The dosage should be escalated in increments of 500 mg weekly based on clinical response and tolerability, up to a maximum dose of 2000 mg once daily. Tablets must be swallowed whole and never crushed, chewed, or split.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy of Glumetza have not been established in pediatric patients.
- Body Weight
- 5-7 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Glumetza is an extended-release tablet designed for adult dosing and is not suitable for infants or young toddlers.
- Body Weight
- 8-10 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Metformin extended-release is not approved for pediatric patients under 10 years of age.
- Body Weight
- 11-15 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Oral tablets cannot be safely split or dissolved for pediatric weight-based dosing in this range.
- Body Weight
- 16-20 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Glumetza is typically not prescribed to pediatric patients in this weight range. Consult a pediatric endocrinologist for alternative therapies.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | N/A | Safety and efficacy of Glumetza have not been established in pediatric patients. |
| 5-7 kg | Not recommended | N/A | Glumetza is an extended-release tablet designed for adult dosing and is not suitable for infants or young toddlers. |
| 8-10 kg | Not recommended | N/A | Metformin extended-release is not approved for pediatric patients under 10 years of age. |
| 11-15 kg | Not recommended | N/A | Oral tablets cannot be safely split or dissolved for pediatric weight-based dosing in this range. |
| 16-20 kg | Not recommended | N/A | Glumetza is typically not prescribed to pediatric patients in this weight range. Consult a pediatric endocrinologist for alternative therapies. |
Formulation
Purpose
Used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
Generic Name
Metformin hydrochlorideScheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.