Nutropin
Nutropin contains somatropin, which is a recombinant human growth hormone (rhGH) equivalent to the growth hormone produced naturally by the human pituitary gland. It stimulates linear growth, skeletal growth, and cellular metabolism.
Dosage by Body Weight
Dosage is highly individualized and must be determined by a specialist based on body weight, specific condition, and patient response. It is administered daily via subcutaneous injection. Injection sites should be rotated daily to prevent localized lipoatrophy.
- Body Weight
- Below 5 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Safety and efficacy in infants below 5 kg have not been established. Any use must be closely supervised by a pediatric endocrinologist.
- Body Weight
- 5-7 kg
- Dose
- 0.15 mg to 0.30 mg daily
- Frequency
- Once daily
- Tracking Notes
- Estimated dose range based on a standard pediatric GHD guideline (0.18 to 0.30 mg/kg/week divided daily). Must be customized by a physician.
- Body Weight
- 8-10 kg
- Dose
- 0.24 mg to 0.43 mg daily
- Frequency
- Once daily
- Tracking Notes
- Estimated dose range based on standard GHD guideline (0.18 to 0.30 mg/kg/week divided daily). Adjusted according to clinical response and growth rate.
- Body Weight
- 11-15 kg
- Dose
- 0.33 mg to 0.64 mg daily
- Frequency
- Once daily
- Tracking Notes
- Estimated dose range based on standard pediatric GHD guideline. Higher doses may be required for conditions like Turner syndrome or CKD.
- Body Weight
- 16-20 kg
- Dose
- 0.48 mg to 0.86 mg daily
- Frequency
- Once daily
- Tracking Notes
- Estimated dose range based on standard pediatric GHD guideline. Monitoring of thyroid function and bone age is highly recommended.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine | Use only if prescribed | Safety and efficacy in infants below 5 kg have not been established. Any use must be closely supervised by a pediatric endocrinologist. |
| 5-7 kg | 0.15 mg to 0.30 mg daily | Once daily | Estimated dose range based on a standard pediatric GHD guideline (0.18 to 0.30 mg/kg/week divided daily). Must be customized by a physician. |
| 8-10 kg | 0.24 mg to 0.43 mg daily | Once daily | Estimated dose range based on standard GHD guideline (0.18 to 0.30 mg/kg/week divided daily). Adjusted according to clinical response and growth rate. |
| 11-15 kg | 0.33 mg to 0.64 mg daily | Once daily | Estimated dose range based on standard pediatric GHD guideline. Higher doses may be required for conditions like Turner syndrome or CKD. |
| 16-20 kg | 0.48 mg to 0.86 mg daily | Once daily | Estimated dose range based on standard pediatric GHD guideline. Monitoring of thyroid function and bone age is highly recommended. |
Formulation
Purpose
Used for the treatment of pediatric patients who have growth failure due to growth hormone deficiency (GHD), chronic kidney disease (CKD) up to the time of renal transplantation, Turner syndrome, and Idiopathic Short Stature (ISS). Also used for growth hormone replacement in adults with growth hormone deficiency.
Generic Name
SomatropinScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.