Omnitrope
Omnitrope is a recombinant human growth hormone (somatropin) that is identical to the natural growth hormone produced by the human body. It stimulates linear growth and increases skeletal growth rate in children, and regulates body composition, fluids, muscle and bone growth, and sugar and fat metabolism in adults.
Dosage by Body Weight
Dosage must be highly individualized for each patient based on body weight or body surface area, clinical response, and serum IGF-1 levels. It is administered daily via subcutaneous injection, rotating injection sites to prevent lipoatrophy.
- Body Weight
- Below 5 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Safety and efficacy in infants under 5 kg must be determined solely by a pediatric endocrinologist.
- Body Weight
- 5-7 kg
- Dose
- 0.12 mg to 0.24 mg
- Frequency
- Once daily
- Tracking Notes
- Administered subcutaneously. Approximate calculation based on standard pediatric GHD dosage of 0.024 to 0.034 mg/kg/day.
- Body Weight
- 8-10 kg
- Dose
- 0.19 mg to 0.34 mg
- Frequency
- Once daily
- Tracking Notes
- Administered subcutaneously. Rotate injection sites daily to prevent tissue breakdown.
- Body Weight
- 11-15 kg
- Dose
- 0.26 mg to 0.51 mg
- Frequency
- Once daily
- Tracking Notes
- Subcutaneous injection. Dose must be adjusted regularly based on growth velocity and laboratory parameters.
- Body Weight
- 16-20 kg
- Dose
- 0.38 mg to 0.68 mg
- Frequency
- Once daily
- Tracking Notes
- Subcutaneous injection. Dosing ranges vary significantly depending on the underlying indication (e.g., GHD vs. Turner Syndrome).
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine | Use only if prescribed | Safety and efficacy in infants under 5 kg must be determined solely by a pediatric endocrinologist. |
| 5-7 kg | 0.12 mg to 0.24 mg | Once daily | Administered subcutaneously. Approximate calculation based on standard pediatric GHD dosage of 0.024 to 0.034 mg/kg/day. |
| 8-10 kg | 0.19 mg to 0.34 mg | Once daily | Administered subcutaneously. Rotate injection sites daily to prevent tissue breakdown. |
| 11-15 kg | 0.26 mg to 0.51 mg | Once daily | Subcutaneous injection. Dose must be adjusted regularly based on growth velocity and laboratory parameters. |
| 16-20 kg | 0.38 mg to 0.68 mg | Once daily | Subcutaneous injection. Dosing ranges vary significantly depending on the underlying indication (e.g., GHD vs. Turner Syndrome). |
Formulation
Purpose
Used to treat growth failure in children due to growth hormone deficiency (GHD), Prader-Willi syndrome, Turner syndrome, Small for Gestational Age (SGA), and SHOX deficiency; and to treat growth hormone deficiency in adults.
Generic Name
SomatropinScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.