Gabastar
Gabastar is an analog of the neurotransmitter gamma-aminobutyric acid (GABA) used primarily to treat neuropathic pain conditions and to control seizures. It works by stabilizing electrical activity in the brain and affecting nerve signals involved in pain.
Dosage by Body Weight
Adult dosage typically starts at 300 mg once daily on Day 1, 300 mg twice daily on Day 2, and 300 mg three times daily on Day 3. Dosage may be titrated up by a healthcare provider. Do not discontinue abruptly.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in patients in this weight range.
- Body Weight
- 5-7 kg
- Dose
- 50 mg to 100 mg per day (divided)
- Frequency
- Three times daily
- Tracking Notes
- Must be initiated under strict specialist supervision at 10-15 mg/kg/day and titrated upward slowly.
- Body Weight
- 8-10 kg
- Dose
- 80 mg to 150 mg per day (divided)
- Frequency
- Three times daily
- Tracking Notes
- Dose adjustment required based on clinical response and tolerance; split into three equal doses.
- Body Weight
- 11-15 kg
- Dose
- 110 mg to 225 mg per day (divided)
- Frequency
- Three times daily
- Tracking Notes
- Ensure maximum interval between doses does not exceed 12 hours.
- Body Weight
- 16-20 kg
- Dose
- 160 mg to 300 mg per day (divided)
- Frequency
- Three times daily
- Tracking Notes
- Titrate carefully over several days to the effective maintenance dose.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | N/A | Safety and efficacy have not been established in patients in this weight range. |
| 5-7 kg | 50 mg to 100 mg per day (divided) | Three times daily | Must be initiated under strict specialist supervision at 10-15 mg/kg/day and titrated upward slowly. |
| 8-10 kg | 80 mg to 150 mg per day (divided) | Three times daily | Dose adjustment required based on clinical response and tolerance; split into three equal doses. |
| 11-15 kg | 110 mg to 225 mg per day (divided) | Three times daily | Ensure maximum interval between doses does not exceed 12 hours. |
| 16-20 kg | 160 mg to 300 mg per day (divided) | Three times daily | Titrate carefully over several days to the effective maintenance dose. |
Formulation
Purpose
Treatment of neuropathic pain (nerve pain) and as an adjunctive therapy in the treatment of partial seizures.
Generic Name
GabapentinScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.