Fresofol
Fresofol is an intravenous anesthetic agent containing propofol. It is a short-acting, general anesthetic used to start and maintain anesthesia, as well as to provide sedation in intensive care or during diagnostic procedures. It must only be administered by trained anesthesiologists or intensive care specialists in a hospital setting.
Dosage by Body Weight
Dosage must be strictly individualized and titrated by a qualified physician. Dose is calculated based on body weight, age, clinical response, and concomitant medications. Continuous monitoring of cardiovascular and respiratory functions is mandatory during administration.
- Body Weight
- Below 5 kg
- Dose
- Contraindicated / Not recommended
- Frequency
- Do not use
- Tracking Notes
- Safety and efficacy of Fresofol in neonates and infants under 1 month of age have not been established.
- Body Weight
- 5-7 kg
- Dose
- 2.5 to 4 mg/kg for induction
- Frequency
- Single slow injection or titrated infusion
- Tracking Notes
- Must be administered only by an anesthesiologist. Dosage should be adjusted based on clinical response and depth of anesthesia.
- Body Weight
- 8-10 kg
- Dose
- 2.5 to 4 mg/kg for induction
- Frequency
- Single slow injection or titrated infusion
- Tracking Notes
- Requires precise administration via infusion pump. Continuous hemodynamic monitoring is mandatory.
- Body Weight
- 11-15 kg
- Dose
- 2.5 to 4 mg/kg for induction
- Frequency
- Single slow injection or titrated infusion
- Tracking Notes
- Maintenance doses range from 9 to 15 mg/kg/hour. Not to be used for ICU sedation in children under 16 years of age.
- Body Weight
- 16-20 kg
- Dose
- 2.5 to 4 mg/kg for induction
- Frequency
- Single slow injection or titrated infusion
- Tracking Notes
- Dose is adjusted according to the depth of anesthesia required. Slower administration is recommended in sensitive patients.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Contraindicated / Not recommended | Do not use | Safety and efficacy of Fresofol in neonates and infants under 1 month of age have not been established. |
| 5-7 kg | 2.5 to 4 mg/kg for induction | Single slow injection or titrated infusion | Must be administered only by an anesthesiologist. Dosage should be adjusted based on clinical response and depth of anesthesia. |
| 8-10 kg | 2.5 to 4 mg/kg for induction | Single slow injection or titrated infusion | Requires precise administration via infusion pump. Continuous hemodynamic monitoring is mandatory. |
| 11-15 kg | 2.5 to 4 mg/kg for induction | Single slow injection or titrated infusion | Maintenance doses range from 9 to 15 mg/kg/hour. Not to be used for ICU sedation in children under 16 years of age. |
| 16-20 kg | 2.5 to 4 mg/kg for induction | Single slow injection or titrated infusion | Dose is adjusted according to the depth of anesthesia required. Slower administration is recommended in sensitive patients. |
Formulation
Purpose
Induction and maintenance of general anesthesia, sedation for mechanically ventilated patients in intensive care, and conscious sedation for surgical and diagnostic procedures.
Generic Name
PropofolScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.