Diprivan
Diprivan (propofol) is an intravenous sedative-hypnotic agent characterized by a rapid onset and a short duration of action. It is used to induce and maintain general anesthesia and to provide sedation in clinical and intensive care environments.
Dosage by Body Weight
Diprivan must only be administered by trained anesthesia providers or clinicians experienced in intensive care. Dosage must be strictly individualized based on clinical response, age, body weight, and patient comorbidities. Typical adult induction doses range from 2 to 2.5 mg/kg IV, followed by continuous infusion for maintenance.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- Not applicable
- Tracking Notes
- Safety and efficacy have not been established in pediatric patients under 2 months of age.
- Body Weight
- 5-7 kg
- Dose
- 2.5 to 3.5 mg/kg IV (Induction)
- Frequency
- Single dose or tailored infusion
- Tracking Notes
- Requires strict clinical monitoring and immediate availability of airway maintenance equipment.
- Body Weight
- 8-10 kg
- Dose
- 2.5 to 3.5 mg/kg IV (Induction)
- Frequency
- Single dose or tailored infusion
- Tracking Notes
- Requires strict clinical monitoring and immediate availability of airway maintenance equipment.
- Body Weight
- 11-15 kg
- Dose
- 2.5 to 3.5 mg/kg IV (Induction)
- Frequency
- Single dose or tailored infusion
- Tracking Notes
- Requires strict clinical monitoring and immediate availability of airway maintenance equipment.
- Body Weight
- 16-20 kg
- Dose
- 2.5 to 3.5 mg/kg IV (Induction)
- Frequency
- Single dose or tailored infusion
- Tracking Notes
- Requires strict clinical monitoring and immediate availability of airway maintenance equipment.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | Not applicable | Safety and efficacy have not been established in pediatric patients under 2 months of age. |
| 5-7 kg | 2.5 to 3.5 mg/kg IV (Induction) | Single dose or tailored infusion | Requires strict clinical monitoring and immediate availability of airway maintenance equipment. |
| 8-10 kg | 2.5 to 3.5 mg/kg IV (Induction) | Single dose or tailored infusion | Requires strict clinical monitoring and immediate availability of airway maintenance equipment. |
| 11-15 kg | 2.5 to 3.5 mg/kg IV (Induction) | Single dose or tailored infusion | Requires strict clinical monitoring and immediate availability of airway maintenance equipment. |
| 16-20 kg | 2.5 to 3.5 mg/kg IV (Induction) | Single dose or tailored infusion | Requires strict clinical monitoring and immediate availability of airway maintenance equipment. |
Formulation
Purpose
Induction and maintenance of general anesthesia, and sedation for mechanically ventilated adults in intensive care units (ICU) or during monitored anesthesia care (MAC).
Generic Name
PropofolScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.