Epilim
Epilim is an antiepileptic and mood-stabilizing medication containing sodium valproate. It works by increasing the brain levels of gamma-aminobutyric acid (GABA), a chemical neurotransmitter that helps suppress abnormal electrical activity in the brain.
Dosage by Body Weight
Dosage must be individualized and carefully titrated by a specialist. The typical starting dose is 10-15 mg/kg body weight daily, increased gradually to an effective maintenance dose of 20-30 mg/kg daily. Epilim should be taken with or after food. Highly restricted in women of childbearing potential due to high risk of birth defects.
- Body Weight
- Below 5 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Treatment in infants must be initiated and monitored strictly under specialist care.
- Body Weight
- 5-7 kg
- Dose
- 50 mg to 100 mg daily
- Frequency
- Divided into 1 or 2 doses
- Tracking Notes
- Initiate at the lowest dose and monitor liver function.
- Body Weight
- 8-10 kg
- Dose
- 100 mg to 150 mg daily
- Frequency
- Divided into 1 or 2 doses
- Tracking Notes
- Liquid or syrup formulations are usually preferred for accurate dosing in this range.
- Body Weight
- 11-15 kg
- Dose
- 150 mg to 300 mg daily
- Frequency
- Divided into 1 or 2 doses
- Tracking Notes
- Adjust doses based on seizure control and clinical tolerance.
- Body Weight
- 16-20 kg
- Dose
- 200 mg to 400 mg daily
- Frequency
- Divided into 1 or 2 doses
- Tracking Notes
- Do not exceed maximum daily limits without consulting a pediatrician.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine | Use only if prescribed | Treatment in infants must be initiated and monitored strictly under specialist care. |
| 5-7 kg | 50 mg to 100 mg daily | Divided into 1 or 2 doses | Initiate at the lowest dose and monitor liver function. |
| 8-10 kg | 100 mg to 150 mg daily | Divided into 1 or 2 doses | Liquid or syrup formulations are usually preferred for accurate dosing in this range. |
| 11-15 kg | 150 mg to 300 mg daily | Divided into 1 or 2 doses | Adjust doses based on seizure control and clinical tolerance. |
| 16-20 kg | 200 mg to 400 mg daily | Divided into 1 or 2 doses | Do not exceed maximum daily limits without consulting a pediatrician. |
Formulation
Purpose
Epilim is used for the treatment of epilepsy (generalized, partial, or other epilepsy types) and the treatment of manic episodes associated with bipolar disorder.
Generic Name
Sodium ValproateScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.