Dolutegravir (Pediatric)
An Integrase Strand Transfer Inhibitor (INSTI). It has a high genetic barrier to resistance and is now the WHO-preferred first-line treatment for children.
Dosage by Body Weight
Dispersible tablets (5mg) are used for infants/children from 3kg and 4 weeks of age. Can be dissolved in water.
- Body Weight
- 3-6 kg
- Dose
- 5 mg
- Frequency
- Once daily
- Tracking Notes
- Preferred 5mg dispersible tablet for infants.
- Body Weight
- 14-20 kg
- Dose
- 25 mg
- Frequency
- Once daily
- Tracking Notes
- Can be taken with or without food.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 3-6 kg | 5 mg | Once daily | Preferred 5mg dispersible tablet for infants. |
| 14-20 kg | 25 mg | Once daily | Can be taken with or without food. |
Formulation
Purpose
First-line antiretroviral treatment for HIV-1.
Generic Name
Dolutegravir (DTG)
Branded Drug Names
Dolutegravir (Pediatric) is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
- Tivicay
- Instgra
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.