Efavirenz

A Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI). Known for causing vivid dreams or dizziness, so it is best taken at bedtime.

Dosage by Body Weight

Dosed by weight bands. Generally for children >3 years and >10 kg. Take on an empty stomach to reduce side effects.

  1. Body Weight
    10-15 kg
    Dose
    200 mg
    Frequency
    Once daily (Bedtime)
    Tracking Notes
    Avoid high-fat meals before taking, as they increase drug levels and toxicity.
  2. Body Weight
    15-20 kg
    Dose
    250 mg
    Frequency
    Once daily (Bedtime)
    Tracking Notes
    Monitor for mood changes or rash.

Formulation

CapsuleTablet

Purpose

Part of combination antiretroviral therapy (ART) for HIV-1.

Generic Name

Efavirenz (EFV)

Branded Drug Names

Efavirenz is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:

Scheduled Drug

Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.

Alternatives

Safety Advice

Alcohol

CAUTION

Efavirenz: Alcohol may worsen dizziness, nausea, dehydration, or liver strain during antiviral treatment. Avoid or limit alcohol.

Pregnancy

SAFE IF PRESCRIBED

Efavirenz: Use during pregnancy only when prescribed; treatment may be important for maternal infection control or prevention of transmission.

Breast Feeding

SAFE IF PRESCRIBED

Efavirenz: Breastfeeding advice depends on the infection and treatment regimen. Use only with healthcare provider guidance.

Driving

CAUTION

Efavirenz: May cause dizziness, fatigue, sleep disturbance, or headache. Avoid driving if alertness is affected.

Liver

CAUTION

Efavirenz: Some antivirals can affect liver function or require monitoring in hepatitis, HIV, or severe illness.

Kidney

CAUTION

Efavirenz: Several antivirals are cleared by the kidneys and may need dose adjustment or hydration. Consult your healthcare provider.

Disclaimer: This information is for educational purposes only. WHO references and weight bands are simplified for tracking and must not replace medical advice. Always consult with a healthcare professional before starting or changing any medication.