Efavirenz
A Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI). Known for causing vivid dreams or dizziness, so it is best taken at bedtime.
Dosage by Body Weight
Dosed by weight bands. Generally for children >3 years and >10 kg. Take on an empty stomach to reduce side effects.
- Body Weight
- 10-15 kg
- Dose
- 200 mg
- Frequency
- Once daily (Bedtime)
- Tracking Notes
- Avoid high-fat meals before taking, as they increase drug levels and toxicity.
- Body Weight
- 15-20 kg
- Dose
- 250 mg
- Frequency
- Once daily (Bedtime)
- Tracking Notes
- Monitor for mood changes or rash.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 10-15 kg | 200 mg | Once daily (Bedtime) | Avoid high-fat meals before taking, as they increase drug levels and toxicity. |
| 15-20 kg | 250 mg | Once daily (Bedtime) | Monitor for mood changes or rash. |
Formulation
Purpose
Part of combination antiretroviral therapy (ART) for HIV-1.
Generic Name
Efavirenz (EFV)Branded Drug Names
Efavirenz is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
CAUTIONEfavirenz: Alcohol may worsen dizziness, nausea, dehydration, or liver strain during antiviral treatment. Avoid or limit alcohol.
Pregnancy
SAFE IF PRESCRIBEDEfavirenz: Use during pregnancy only when prescribed; treatment may be important for maternal infection control or prevention of transmission.
Breast Feeding
SAFE IF PRESCRIBEDEfavirenz: Breastfeeding advice depends on the infection and treatment regimen. Use only with healthcare provider guidance.
Driving
CAUTIONEfavirenz: May cause dizziness, fatigue, sleep disturbance, or headache. Avoid driving if alertness is affected.
Liver
CAUTIONEfavirenz: Some antivirals can affect liver function or require monitoring in hepatitis, HIV, or severe illness.
Kidney
CAUTIONEfavirenz: Several antivirals are cleared by the kidneys and may need dose adjustment or hydration. Consult your healthcare provider.