Azasan
Azasan (azathioprine) is an immunosuppressive antimetabolite. It works by suppressing the body's immune system, which helps prevent transplant rejection and reduces the inflammation, joint pain, and swelling associated with severe rheumatoid arthritis.
Dosage by Body Weight
Azasan dosage is highly individualized and typically calculated based on body weight. For kidney transplant, starting doses are usually 3 to 5 mg/kg daily. For rheumatoid arthritis, the starting dose is approximately 1 mg/kg daily, which may be increased if needed. Frequent blood counts are necessary to monitor for toxicity.
- Body Weight
- Below 5 kg
- Dose
- 1 to 5 mg/kg daily
- Frequency
- Once daily
- Tracking Notes
- Requires strict specialist supervision and precise pediatric dosing calculations.
- Body Weight
- 5-7 kg
- Dose
- 5 to 35 mg daily
- Frequency
- Once daily or in divided doses
- Tracking Notes
- Calculated based on 1-5 mg/kg daily range. Close hematologic monitoring is essential.
- Body Weight
- 8-10 kg
- Dose
- 8 to 50 mg daily
- Frequency
- Once daily or in divided doses
- Tracking Notes
- Calculated based on 1-5 mg/kg daily range. Adjust dose based on response and blood counts.
- Body Weight
- 11-15 kg
- Dose
- 11 to 75 mg daily
- Frequency
- Once daily or in divided doses
- Tracking Notes
- Calculated based on 1-5 mg/kg daily range. Monitor liver and kidney functions regularly.
- Body Weight
- 16-20 kg
- Dose
- 16 to 100 mg daily
- Frequency
- Once daily or in divided doses
- Tracking Notes
- Calculated based on 1-5 mg/kg daily range. Limit dose to the minimum effective amount.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | 1 to 5 mg/kg daily | Once daily | Requires strict specialist supervision and precise pediatric dosing calculations. |
| 5-7 kg | 5 to 35 mg daily | Once daily or in divided doses | Calculated based on 1-5 mg/kg daily range. Close hematologic monitoring is essential. |
| 8-10 kg | 8 to 50 mg daily | Once daily or in divided doses | Calculated based on 1-5 mg/kg daily range. Adjust dose based on response and blood counts. |
| 11-15 kg | 11 to 75 mg daily | Once daily or in divided doses | Calculated based on 1-5 mg/kg daily range. Monitor liver and kidney functions regularly. |
| 16-20 kg | 16 to 100 mg daily | Once daily or in divided doses | Calculated based on 1-5 mg/kg daily range. Limit dose to the minimum effective amount. |
Formulation
Purpose
Used to prevent organ rejection in kidney transplants and to treat severe, active rheumatoid arthritis.
Generic Name
AzathioprineScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.