Alfacal
Alfacal contains Alfacalcidol, which is a synthetic analogue of Vitamin D3. It is rapidly converted in the liver to 1,25-dihydroxyvitamin D3 (calcitriol), the active form of Vitamin D. Unlike standard Vitamin D, it does not require activation by the kidneys, making it highly effective for patients with impaired renal function to help regulate calcium and phosphate metabolism.
Dosage by Body Weight
Dosage must be strictly individualized under medical supervision. It is determined and adjusted based on regular monitoring of serum calcium, phosphate, and alkaline phosphatase levels. Usually administered once daily with or without food.
- Body Weight
- Below 5 kg
- Dose
- 0.05 to 0.1 mcg per kg daily
- Frequency
- Once daily
- Tracking Notes
- Must be initiated and monitored strictly by a pediatric endocrinologist or nephrologist.
- Body Weight
- 5-7 kg
- Dose
- 0.25 mcg daily
- Frequency
- Once daily
- Tracking Notes
- Adjust dosage based on regular blood calcium level monitoring.
- Body Weight
- 8-10 kg
- Dose
- 0.25 to 0.5 mcg daily
- Frequency
- Once daily
- Tracking Notes
- Maintain adequate calcium intake through diet or supplements as advised.
- Body Weight
- 11-15 kg
- Dose
- 0.5 mcg daily
- Frequency
- Once daily
- Tracking Notes
- Monitor urinary calcium excretion periodically to prevent hypercalciuria.
- Body Weight
- 16-20 kg
- Dose
- 0.5 to 1 mcg daily
- Frequency
- Once daily
- Tracking Notes
- Doses may be titrated upward carefully depending on therapeutic response and lab parameters.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | 0.05 to 0.1 mcg per kg daily | Once daily | Must be initiated and monitored strictly by a pediatric endocrinologist or nephrologist. |
| 5-7 kg | 0.25 mcg daily | Once daily | Adjust dosage based on regular blood calcium level monitoring. |
| 8-10 kg | 0.25 to 0.5 mcg daily | Once daily | Maintain adequate calcium intake through diet or supplements as advised. |
| 11-15 kg | 0.5 mcg daily | Once daily | Monitor urinary calcium excretion periodically to prevent hypercalciuria. |
| 16-20 kg | 0.5 to 1 mcg daily | Once daily | Doses may be titrated upward carefully depending on therapeutic response and lab parameters. |
Formulation
Purpose
Used to treat disorders of calcium metabolism associated with chronic kidney disease (renal osteodystrophy), hypoparathyroidism, pseudohypoparathyroidism, nutritional or metabolic rickets, osteomalacia, and postmenopausal osteoporosis.
Generic Name
AlfacalcidolScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.