Akurit
Akurit is a combination antibiotic consisting of Rifampicin and Isoniazid. It is used in the treatment and prevention of tuberculosis. Rifampicin prevents bacterial growth by inhibiting RNA synthesis, while Isoniazid prevents cell wall synthesis of the tubercle bacilli.
Dosage by Body Weight
Take this medication on an empty stomach, either 1 hour before or 2 hours after meals, with a full glass of water. It must be taken regularly without skipping doses to prevent drug resistance. Consult your doctor for exact dosage based on the clinical condition.
- Body Weight
- Below 5 kg
- Dose
- Dose must be individualized by a pediatrician
- Frequency
- Once daily
- Tracking Notes
- Not routinely recommended in standard fixed-dose tablet form for this weight range. Requires liquid or specialized infant formulations.
- Body Weight
- 5-7 kg
- Dose
- 1 dispersible tablet (Kid formulation: Rifampicin 75mg / Isoniazid 50mg)
- Frequency
- Once daily on an empty stomach
- Tracking Notes
- Disperse the tablet in a small amount of boiled and cooled water before administration.
- Body Weight
- 8-10 kg
- Dose
- 1.5 dispersible tablets (Kid formulation)
- Frequency
- Once daily on an empty stomach
- Tracking Notes
- Monitor liver function tests periodically during therapy.
- Body Weight
- 11-15 kg
- Dose
- 2 dispersible tablets (Kid formulation)
- Frequency
- Once daily on an empty stomach
- Tracking Notes
- Ensure complete course completion even if symptoms improve.
- Body Weight
- 16-20 kg
- Dose
- 3 dispersible tablets (Kid formulation) or customized adult dose
- Frequency
- Once daily on an empty stomach
- Tracking Notes
- Watch for side effects such as dark urine, yellowing of skin/eyes, or persistent nausea.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Dose must be individualized by a pediatrician | Once daily | Not routinely recommended in standard fixed-dose tablet form for this weight range. Requires liquid or specialized infant formulations. |
| 5-7 kg | 1 dispersible tablet (Kid formulation: Rifampicin 75mg / Isoniazid 50mg) | Once daily on an empty stomach | Disperse the tablet in a small amount of boiled and cooled water before administration. |
| 8-10 kg | 1.5 dispersible tablets (Kid formulation) | Once daily on an empty stomach | Monitor liver function tests periodically during therapy. |
| 11-15 kg | 2 dispersible tablets (Kid formulation) | Once daily on an empty stomach | Ensure complete course completion even if symptoms improve. |
| 16-20 kg | 3 dispersible tablets (Kid formulation) or customized adult dose | Once daily on an empty stomach | Watch for side effects such as dark urine, yellowing of skin/eyes, or persistent nausea. |
Formulation
Tablet
Purpose
Treatment of active tuberculosis (TB) infections caused by Mycobacterium tuberculosis.
Generic Name
Rifampicin + IsoniazidScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.