Acyclovir

Acyclovir is a synthetic nucleoside analogue active against herpesviruses. It works by slowing the growth and spread of the herpes virus in the body, helping the body fight off the infection. While it reduces the severity and duration of outbreaks, it is not a cure for herpes.

Dosage by Body Weight

Dosage is highly dependent on the type of infection (e.g., chickenpox, shingles, or genital herpes), patient age, and renal function. Pediatric dosing for chickenpox is typically based on body weight (usually 20 mg/kg per dose, up to 800 mg, taken 4 times daily for 5 days). Always follow a pediatrician's specific prescription.

  1. Body Weight
    Below 5 kg
    Dose
    Requires specialist calculation
    Frequency
    Use only if prescribed
    Tracking Notes
    Safety and efficacy in infants under 3 months are not fully established. Dosing must be carefully managed by a pediatrician.
  2. Body Weight
    5-7 kg
    Dose
    100 mg to 140 mg (approx. 2.5 mL to 3.5 mL of 200mg/5mL oral suspension)
    Frequency
    4 times daily for 5 days
    Tracking Notes
    Based on standard pediatric chickenpox dosing of 20 mg/kg/dose. Maintain excellent hydration.
  3. Body Weight
    8-10 kg
    Dose
    160 mg to 200 mg (approx. 4 mL to 5 mL of 200mg/5mL oral suspension)
    Frequency
    4 times daily for 5 days
    Tracking Notes
    Shake the suspension well before measuring the dose. Use an accurate oral syringe.
  4. Body Weight
    11-15 kg
    Dose
    220 mg to 300 mg (approx. 5.5 mL to 7.5 mL of 200mg/5mL oral suspension)
    Frequency
    4 times daily for 5 days
    Tracking Notes
    Administer doses at evenly spaced intervals. Complete the full course of treatment.
  5. Body Weight
    16-20 kg
    Dose
    320 mg to 400 mg (approx. 8 mL to 10 mL of 200mg/5mL oral suspension, or half/full 400mg tablet if appropriate for child's swallowing ability)
    Frequency
    4 times daily for 5 days
    Tracking Notes
    Maximum single pediatric dose is typically 800 mg. Consult a physician if symptoms do not improve.

Formulation

TabletCapsuleOral SuspensionCreamOintmentIntravenous Infusion

Purpose

Treatment of viral infections caused by the herpes simplex virus (genital herpes, cold sores), varicella-zoster virus (shingles, chickenpox), and herpes zoster.

Generic Name

Acyclovir

Branded Drug Names

Acyclovir is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:

Scheduled Drug

Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.

Alternatives

Disclaimer: This information is for educational purposes only. WHO references and weight bands are simplified for tracking and must not replace medical advice. Always consult with a healthcare professional before starting or changing any medication.