Urea
Urea is a keratolytic agent that promotes hydration and breakdown of hyperkeratotic skin. It works by dissolving the intracellular matrix of the stratum corneum, facilitating the softening and shedding of scaly skin cells, and enhancing water-binding capacity in the skin.
Dosage by Body Weight
Apply topically to the affected skin areas typically 1 to 3 times daily, or as directed by a healthcare provider. Rub in thoroughly until absorbed. Wash hands after application unless treating the hands.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- Do not use
- Tracking Notes
- Safety and efficacy in neonates and small infants have not been established. Avoid use unless explicitly prescribed by a pediatrician.
- Body Weight
- 5-7 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Consult a pediatrician. If approved, use only low-concentration formulations (e.g., 10% or less) and apply very sparingly.
- Body Weight
- 8-10 kg
- Dose
- Apply sparingly
- Frequency
- 1-2 times daily
- Tracking Notes
- Use low-strength formulations (e.g., 10%). Avoid application to face, flexures, or broken skin.
- Body Weight
- 11-15 kg
- Dose
- Apply a thin layer
- Frequency
- 1-2 times daily
- Tracking Notes
- Avoid sensitive areas, eyes, and mucous membranes. Discontinue if irritation occurs.
- Body Weight
- 16-20 kg
- Dose
- Apply a thin layer
- Frequency
- 1-2 times daily
- Tracking Notes
- Ensure child does not rub the medication into their eyes. Wash hands thoroughly after application.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | Do not use | Safety and efficacy in neonates and small infants have not been established. Avoid use unless explicitly prescribed by a pediatrician. |
| 5-7 kg | Not routine | Use only if prescribed | Consult a pediatrician. If approved, use only low-concentration formulations (e.g., 10% or less) and apply very sparingly. |
| 8-10 kg | Apply sparingly | 1-2 times daily | Use low-strength formulations (e.g., 10%). Avoid application to face, flexures, or broken skin. |
| 11-15 kg | Apply a thin layer | 1-2 times daily | Avoid sensitive areas, eyes, and mucous membranes. Discontinue if irritation occurs. |
| 16-20 kg | Apply a thin layer | 1-2 times daily | Ensure child does not rub the medication into their eyes. Wash hands thoroughly after application. |
Formulation
Purpose
Used topically to hydrate, soften, and promote the shedding of dry, rough, or hyperkeratotic skin conditions such as eczema, psoriasis, corns, calluses, and ichthyosis. Also used to aid in the debridement of damaged or dystrophic nails.
Generic Name
UreaBranded Drug Names
Urea is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.