Gentamicin
Potent antibiotic that inhibits bacterial protein synthesis. Requires careful monitoring because it can be toxic to the ears and kidneys.
Dosage by Body Weight
In neonates and children, once-daily dosing (5-7.5 mg/kg) is now standard to reduce toxicity.
- Body Weight
- 3-5 kg (Newborn)
- Dose
- 15 mg to 25 mg
- Frequency
- Every 24-36 hours
- Tracking Notes
- Dosing interval depends on the gestational age and renal function.
- Body Weight
- 6-15 kg
- Dose
- 45 mg to 100 mg
- Frequency
- Once daily
- Tracking Notes
- Blood levels (peak/trough) should be monitored if used >48 hours.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 3-5 kg (Newborn) | 15 mg to 25 mg | Every 24-36 hours | Dosing interval depends on the gestational age and renal function. |
| 6-15 kg | 45 mg to 100 mg | Once daily | Blood levels (peak/trough) should be monitored if used >48 hours. |
Formulation
Purpose
Aminoglycoside antibiotic used for severe Gram-negative infections (sepsis, UTI).
Generic Name
Gentamicin SulfateBranded Drug Names
Gentamicin is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
CAUTIONGentamicin: Alcohol may worsen infection-related dehydration, dizziness, or stomach upset. Avoid or limit alcohol during antibiotic treatment.
Pregnancy
SAFE IF PRESCRIBEDGentamicin: Use during pregnancy only when prescribed for a bacterial infection; the prescriber will choose the safest suitable antibiotic.
Breast Feeding
SAFE IF PRESCRIBEDGentamicin: Many antibiotics are compatible with breastfeeding when prescribed, but monitor the infant for diarrhea, rash, or thrush.
Driving
SAFEGentamicin: Usually does not affect driving, but dizziness, weakness, or illness symptoms can occur. Avoid driving if affected.
Liver
CAUTIONGentamicin: Use caution in liver disease or if jaundice, dark urine, or severe fatigue occurs during treatment.
Kidney
CAUTIONGentamicin: Some antibiotics require dose adjustment or monitoring in kidney disease. Use exactly as prescribed.