Clofazimine
A dye that has antimycobacterial properties. It is a key part of the WHO multidrug therapy (MDT) for leprosy.
Dosage by Body Weight
Pediatric leprosy dose (multibacillary): 50 mg every other day, plus a monthly 150 mg supervised dose.
- Body Weight
- Children >10 kg
- Dose
- 50 mg
- Frequency
- Every other day
- Tracking Notes
- May cause a reddish-brown discoloration of the skin and eyes.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Children >10 kg | 50 mg | Every other day | May cause a reddish-brown discoloration of the skin and eyes. |
Formulation
Purpose
Treatment of Multibacillary Leprosy and MDR-Tuberculosis.
Generic Name
ClofazimineBranded Drug Names
Clofazimine is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
CAUTIONClofazimine: Alcohol may increase dizziness, stomach upset, dehydration, or other side effects. Avoid or limit alcohol and follow medical advice.
Pregnancy
SAFE IF PRESCRIBEDClofazimine: Use during pregnancy only if prescribed after a healthcare provider weighs the benefits and risks.
Breast Feeding
SAFE IF PRESCRIBEDClofazimine: Use while breastfeeding only with healthcare provider guidance, especially for repeated or long-term treatment.
Driving
CAUTIONClofazimine: This medicine may cause dizziness, drowsiness, weakness, or blurred vision in some people. Avoid driving if affected.
Liver
CAUTIONClofazimine: Use with caution in liver disease and consult your healthcare provider if you have abnormal liver tests or jaundice.
Kidney
CAUTIONClofazimine: Use with caution in kidney disease because dose adjustment or monitoring may be needed for some patients.