Ciclesonide
Ciclesonide is an inhaled glucocorticoid and prodrug, which is enzymatically converted to its active metabolite (des-isobutyryl-ciclesonide) in the lungs or nasal mucosa. This localized activation helps minimize systemic absorption and reduces the risk of typical corticosteroid-related side effects.
Dosage by Body Weight
Dosage must be individualized. For asthma (inhalation): Adults and adolescents (12 years and older) typically start at 80 mcg to 160 mcg once or twice daily, with a maximum dose of 320 mcg twice daily. For allergic rhinitis (nasal spray): Typically 200 mcg daily administered as 2 sprays (50 mcg per spray) in each nostril once daily.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in infants and neonates.
- Body Weight
- 5-7 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Not indicated for use in this weight range as it usually correlates to an age below the approved pediatric limit.
- Body Weight
- 8-10 kg
- Dose
- Consult pediatrician
- Frequency
- Consult pediatrician
- Tracking Notes
- Generally not approved for children under 2 to 6 years of age (depending on the formulation and country guidelines).
- Body Weight
- 11-15 kg
- Dose
- 80 mcg (inhalation)
- Frequency
- Once daily
- Tracking Notes
- Only for children who meet the minimum age requirement (typically 6 years and older for asthma maintenance) and under strict pediatric supervision.
- Body Weight
- 16-20 kg
- Dose
- 80 mcg (inhalation) or 100 mcg (nasal)
- Frequency
- Once daily
- Tracking Notes
- Dosage should be kept to the lowest effective level to maintain control of symptoms. Use of a spacer is recommended for younger children using the inhaler.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | N/A | Safety and efficacy have not been established in infants and neonates. |
| 5-7 kg | Not recommended | N/A | Not indicated for use in this weight range as it usually correlates to an age below the approved pediatric limit. |
| 8-10 kg | Consult pediatrician | Consult pediatrician | Generally not approved for children under 2 to 6 years of age (depending on the formulation and country guidelines). |
| 11-15 kg | 80 mcg (inhalation) | Once daily | Only for children who meet the minimum age requirement (typically 6 years and older for asthma maintenance) and under strict pediatric supervision. |
| 16-20 kg | 80 mcg (inhalation) or 100 mcg (nasal) | Once daily | Dosage should be kept to the lowest effective level to maintain control of symptoms. Use of a spacer is recommended for younger children using the inhaler. |
Formulation
Purpose
Maintenance treatment of asthma and management of seasonal and perennial allergic rhinitis symptoms.
Generic Name
CiclesonideBranded Drug Names
Ciclesonide is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.