Cariprazine
Cariprazine is an atypical antipsychotic. It is believed to exert its efficacy through a combination of partial agonist activity at central dopamine D2, D3, and serotonin 5-HT1A receptors, and antagonist activity at serotonin 5-HT2A receptors. It has particularly high in vitro affinity for the dopamine D3 receptor.
Dosage by Body Weight
The recommended starting dose is 1.5 mg taken orally once daily. Dosage may be increased to a maximum of 6 mg once daily based on clinical response and tolerability. Dosage is not determined by body weight, and it is not approved for pediatric use.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and effectiveness in pediatric patients have not been established.
- Body Weight
- 5-7 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and effectiveness in pediatric patients have not been established.
- Body Weight
- 8-10 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and effectiveness in pediatric patients have not been established.
- Body Weight
- 11-15 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and effectiveness in pediatric patients have not been established.
- Body Weight
- 16-20 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and effectiveness in pediatric patients have not been established.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | N/A | Safety and effectiveness in pediatric patients have not been established. |
| 5-7 kg | Not recommended | N/A | Safety and effectiveness in pediatric patients have not been established. |
| 8-10 kg | Not recommended | N/A | Safety and effectiveness in pediatric patients have not been established. |
| 11-15 kg | Not recommended | N/A | Safety and effectiveness in pediatric patients have not been established. |
| 16-20 kg | Not recommended | N/A | Safety and effectiveness in pediatric patients have not been established. |
Formulation
Purpose
Used for the treatment of schizophrenia, acute manic or mixed episodes associated with bipolar I disorder, and depressive episodes associated with bipolar I disorder (bipolar depression).
Generic Name
CariprazineBranded Drug Names
Cariprazine is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.