Xaparin
Xaparin contains Enoxaparin, a low molecular weight heparin (LMWH). It works by accelerating the inhibition of clotting factors Xa and IIa, preventing the formation and propagation of blood clots without significantly affecting platelet aggregation or systemic coagulation parameters at recommended doses.
Dosage by Body Weight
Must be administered subcutaneously (typically in the abdomen) or intravenously in specific acute coronary indications. Dosage must be highly individualized based on the specific clinical indication, patient body weight, and renal function. Do not inject intramuscularly.
- Body Weight
- Below 5 kg
- Dose
- 1.5 mg/kg (Neonates/Infants)
- Frequency
- Every 12 hours
- Tracking Notes
- Pediatric dosing requires strict specialist supervision and frequent anti-Factor Xa level monitoring.
- Body Weight
- 5-7 kg
- Dose
- 1 mg/kg (Treatment) or 0.5 mg/kg (Prophylaxis)
- Frequency
- Every 12 hours
- Tracking Notes
- Use with caution. Requires precise measurement using a tuberculin or low-volume syringe.
- Body Weight
- 8-10 kg
- Dose
- 1 mg/kg (Treatment) or 0.5 mg/kg (Prophylaxis)
- Frequency
- Every 12 hours
- Tracking Notes
- Adjust doses in patients with impaired renal function (creatinine clearance < 30 mL/min).
- Body Weight
- 11-15 kg
- Dose
- 1 mg/kg (Treatment) or 0.5 mg/kg (Prophylaxis)
- Frequency
- Every 12 hours
- Tracking Notes
- Monitor for any signs of unusual bleeding or bruising. Rotate injection sites daily.
- Body Weight
- 16-20 kg
- Dose
- 1 mg/kg (Treatment) or 0.5 mg/kg (Prophylaxis)
- Frequency
- Every 12 hours
- Tracking Notes
- Standard pediatric therapeutic regimen. Ensure anti-Xa levels are monitored periodically.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | 1.5 mg/kg (Neonates/Infants) | Every 12 hours | Pediatric dosing requires strict specialist supervision and frequent anti-Factor Xa level monitoring. |
| 5-7 kg | 1 mg/kg (Treatment) or 0.5 mg/kg (Prophylaxis) | Every 12 hours | Use with caution. Requires precise measurement using a tuberculin or low-volume syringe. |
| 8-10 kg | 1 mg/kg (Treatment) or 0.5 mg/kg (Prophylaxis) | Every 12 hours | Adjust doses in patients with impaired renal function (creatinine clearance < 30 mL/min). |
| 11-15 kg | 1 mg/kg (Treatment) or 0.5 mg/kg (Prophylaxis) | Every 12 hours | Monitor for any signs of unusual bleeding or bruising. Rotate injection sites daily. |
| 16-20 kg | 1 mg/kg (Treatment) or 0.5 mg/kg (Prophylaxis) | Every 12 hours | Standard pediatric therapeutic regimen. Ensure anti-Xa levels are monitored periodically. |
Formulation
Purpose
Prevention and treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE), prevention of clotting during hemodialysis, and management of acute coronary syndrome (including unstable angina and myocardial infarction).
Generic Name
Enoxaparin SodiumScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.