Clexane
Clexane contains enoxaparin sodium, which is a low-molecular-weight heparin (LMWH). It works by inhibiting clotting factors (mainly Factor Xa) in the blood to prevent the formation of blood clots and to stop existing clots from expanding, allowing the body to naturally break them down.
Dosage by Body Weight
Administered via subcutaneous injection (or intravenously in acute cardiac settings). Dosage is highly individualized based on body weight, medical indication, and renal function. Pediatric dosing must be calculated strictly on a mg/kg basis and monitored by a specialist.
- Body Weight
- Below 5 kg
- Dose
- Requires exact weight-based calculation (typically 1.5 mg/kg for neonates, 1 mg/kg for older infants)
- Frequency
- Every 12 hours
- Tracking Notes
- Strict monitoring of anti-Factor Xa levels is essential. Do not use standard prefilled syringe graduations.
- Body Weight
- 5-7 kg
- Dose
- 5 mg to 7 mg (calculated at 1 mg/kg)
- Frequency
- Every 12 hours
- Tracking Notes
- Use a low-volume syringe for precise measurement. Rotate injection sites daily.
- Body Weight
- 8-10 kg
- Dose
- 8 mg to 10 mg (calculated at 1 mg/kg)
- Frequency
- Every 12 hours
- Tracking Notes
- Adjust dosage downwards if severe renal impairment is present.
- Body Weight
- 11-15 kg
- Dose
- 11 mg to 15 mg (calculated at 1 mg/kg)
- Frequency
- Every 12 hours
- Tracking Notes
- Prophylactic dosing is lower, typically 0.5 mg/kg every 12 to 24 hours.
- Body Weight
- 16-20 kg
- Dose
- 16 mg to 20 mg (calculated at 1 mg/kg)
- Frequency
- Every 12 hours
- Tracking Notes
- Monitor for any unusual bruising, bleeding, or pain at the injection site.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Requires exact weight-based calculation (typically 1.5 mg/kg for neonates, 1 mg/kg for older infants) | Every 12 hours | Strict monitoring of anti-Factor Xa levels is essential. Do not use standard prefilled syringe graduations. |
| 5-7 kg | 5 mg to 7 mg (calculated at 1 mg/kg) | Every 12 hours | Use a low-volume syringe for precise measurement. Rotate injection sites daily. |
| 8-10 kg | 8 mg to 10 mg (calculated at 1 mg/kg) | Every 12 hours | Adjust dosage downwards if severe renal impairment is present. |
| 11-15 kg | 11 mg to 15 mg (calculated at 1 mg/kg) | Every 12 hours | Prophylactic dosing is lower, typically 0.5 mg/kg every 12 to 24 hours. |
| 16-20 kg | 16 mg to 20 mg (calculated at 1 mg/kg) | Every 12 hours | Monitor for any unusual bruising, bleeding, or pain at the injection site. |
Formulation
Purpose
Prevention and treatment of deep vein thrombosis (DVT), pulmonary embolism (PE), acute coronary syndrome, and prevention of clot formation in the extracorporeal circulation during hemodialysis.
Generic Name
Enoxaparin sodiumScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.