Vfend
Vfend (voriconazole) is a prescription triazole antifungal medicine used to treat a wide variety of serious, systemic fungal infections by inhibiting fungal cell wall synthesis.
Dosage by Body Weight
Dosage depends on age, weight, and the type of infection. Usually initiated with an intravenous loading dose followed by oral maintenance therapy. Oral forms should be taken at least one hour before or after a meal.
- Body Weight
- Below 5 kg
- Dose
- Safety and efficacy not established
- Frequency
- Not recommended
- Tracking Notes
- Generally not recommended for pediatric patients under 2 years of age unless prescribed under strict specialist guidance.
- Body Weight
- 5-7 kg
- Dose
- 45 mg to 63 mg (approx. 9 mg/kg)
- Frequency
- Every 12 hours
- Tracking Notes
- Based on standard pediatric oral dosing guidelines of 9 mg/kg. Utilize oral suspension for precise dosing.
- Body Weight
- 8-10 kg
- Dose
- 72 mg to 90 mg (approx. 9 mg/kg)
- Frequency
- Every 12 hours
- Tracking Notes
- Monitor liver function and serum drug levels closely during therapy.
- Body Weight
- 11-15 kg
- Dose
- 100 mg to 135 mg (approx. 9 mg/kg)
- Frequency
- Every 12 hours
- Tracking Notes
- Administer on an empty stomach at least one hour before or one hour after meals.
- Body Weight
- 16-20 kg
- Dose
- 144 mg to 180 mg (approx. 9 mg/kg)
- Frequency
- Every 12 hours
- Tracking Notes
- Do not exceed maximum pediatric oral dose of 350 mg every 12 hours.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Safety and efficacy not established | Not recommended | Generally not recommended for pediatric patients under 2 years of age unless prescribed under strict specialist guidance. |
| 5-7 kg | 45 mg to 63 mg (approx. 9 mg/kg) | Every 12 hours | Based on standard pediatric oral dosing guidelines of 9 mg/kg. Utilize oral suspension for precise dosing. |
| 8-10 kg | 72 mg to 90 mg (approx. 9 mg/kg) | Every 12 hours | Monitor liver function and serum drug levels closely during therapy. |
| 11-15 kg | 100 mg to 135 mg (approx. 9 mg/kg) | Every 12 hours | Administer on an empty stomach at least one hour before or one hour after meals. |
| 16-20 kg | 144 mg to 180 mg (approx. 9 mg/kg) | Every 12 hours | Do not exceed maximum pediatric oral dose of 350 mg every 12 hours. |
Formulation
TabletOral SuspensionInjection
Purpose
Treatment of serious invasive fungal infections, including invasive aspergillosis, candidemia, esophageal candidiasis, and serious infections caused by Scedosporium and Fusarium species.
Generic Name
VoriconazoleScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.