Trileptal
Trileptal (oxcarbazepine) is an anticonvulsant or antiepileptic drug. It works by stabilizing hyperexcited neural membranes, inhibiting repetitive neuronal firing, and diminishing oscillatory bursts of action potentials, primarily by blocking voltage-sensitive sodium channels.
Dosage by Body Weight
Adult starting dose is typically 300 mg twice daily. Pediatric dosing for children aged 2 to 16 years is based on body weight, starting at 8 to 10 mg/kg/day divided into two doses. Doses should be adjusted gradually based on clinical response.
- Body Weight
- Below 5 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Safety and effectiveness in pediatric patients below the age of 2 years (or weighing under standard limits) have not been established.
- Body Weight
- 5-7 kg
- Dose
- 40 mg to 70 mg daily (divided twice daily)
- Frequency
- Two times daily (every 12 hours)
- Tracking Notes
- Starting dose calculation. Standard maintenance target range is 150 mg to 320 mg daily, divided twice daily.
- Body Weight
- 8-10 kg
- Dose
- 80 mg to 100 mg daily (divided twice daily)
- Frequency
- Two times daily (every 12 hours)
- Tracking Notes
- Starting dose calculation. Standard maintenance target range is 300 mg to 460 mg daily, divided twice daily.
- Body Weight
- 11-15 kg
- Dose
- 110 mg to 150 mg daily (divided twice daily)
- Frequency
- Two times daily (every 12 hours)
- Tracking Notes
- Starting dose calculation. Standard maintenance target range is 440 mg to 690 mg daily, divided twice daily.
- Body Weight
- 16-20 kg
- Dose
- 160 mg to 200 mg daily (divided twice daily)
- Frequency
- Two times daily (every 12 hours)
- Tracking Notes
- Starting dose calculation. Standard maintenance target range is 640 mg to 920 mg daily, divided twice daily.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine | Use only if prescribed | Safety and effectiveness in pediatric patients below the age of 2 years (or weighing under standard limits) have not been established. |
| 5-7 kg | 40 mg to 70 mg daily (divided twice daily) | Two times daily (every 12 hours) | Starting dose calculation. Standard maintenance target range is 150 mg to 320 mg daily, divided twice daily. |
| 8-10 kg | 80 mg to 100 mg daily (divided twice daily) | Two times daily (every 12 hours) | Starting dose calculation. Standard maintenance target range is 300 mg to 460 mg daily, divided twice daily. |
| 11-15 kg | 110 mg to 150 mg daily (divided twice daily) | Two times daily (every 12 hours) | Starting dose calculation. Standard maintenance target range is 440 mg to 690 mg daily, divided twice daily. |
| 16-20 kg | 160 mg to 200 mg daily (divided twice daily) | Two times daily (every 12 hours) | Starting dose calculation. Standard maintenance target range is 640 mg to 920 mg daily, divided twice daily. |
Formulation
Purpose
Used as monotherapy or adjunctive therapy in the treatment of partial-onset seizures in adults and children 2 years of age and older.
Generic Name
OxcarbazepineScheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.