Tizanidine
A short-acting central alpha-2 adrenergic agonist. It reduces spasticity by increasing presynaptic inhibition of motor neurons.
Dosage by Body Weight
Pediatric use is off-label. Starts at very low doses (1-2 mg at bedtime) and titrated. Monitor for hypotension.
- Body Weight
- Adolescents
- Dose
- 2 mg
- Frequency
- Once daily (at night)
- Tracking Notes
- Can cause dry mouth and drowsiness.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Adolescents | 2 mg | Once daily (at night) | Can cause dry mouth and drowsiness. |
Formulation
Tablet
Purpose
Muscle relaxant for spasticity associated with Cerebral Palsy or spinal cord injury.
Generic Name
Tizanidine Hydrochloride
Branded Drug Names
Tizanidine is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
- Zanaflex
- Tizpa
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
BaclofenDiazepam