Tizanidine
A short-acting central alpha-2 adrenergic agonist. It reduces spasticity by increasing presynaptic inhibition of motor neurons.
Dosage by Body Weight
Pediatric use is off-label. Starts at very low doses (1-2 mg at bedtime) and titrated. Monitor for hypotension.
- Body Weight
- Adolescents
- Dose
- 2 mg
- Frequency
- Once daily (at night)
- Tracking Notes
- Can cause dry mouth and drowsiness.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Adolescents | 2 mg | Once daily (at night) | Can cause dry mouth and drowsiness. |
Formulation
Purpose
Muscle relaxant for spasticity associated with Cerebral Palsy or spinal cord injury.
Generic Name
Tizanidine HydrochlorideBranded Drug Names
Tizanidine is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
CAUTIONTizanidine: Alcohol may increase dizziness, stomach upset, dehydration, or other side effects. Avoid or limit alcohol and follow medical advice.
Pregnancy
SAFE IF PRESCRIBEDTizanidine: Use during pregnancy only if prescribed after a healthcare provider weighs the benefits and risks.
Breast Feeding
SAFE IF PRESCRIBEDTizanidine: Use while breastfeeding only with healthcare provider guidance, especially for repeated or long-term treatment.
Driving
CAUTIONTizanidine: This medicine may cause dizziness, drowsiness, weakness, or blurred vision in some people. Avoid driving if affected.
Liver
CAUTIONTizanidine: Use with caution in liver disease and consult your healthcare provider if you have abnormal liver tests or jaundice.
Kidney
CAUTIONTizanidine: Use with caution in kidney disease because dose adjustment or monitoring may be needed for some patients.