Rofact
Rofact is a brand of rifampin (rifampicin), a bactericidal antibiotic that inhibits bacterial RNA synthesis. It is highly active against Mycobacterium tuberculosis. A notable and harmless side effect is that it may color urine, sweat, tears, and saliva a reddish-orange.
Dosage by Body Weight
Take on an empty stomach, 1 hour before or 2 hours after meals, with a full glass of water. Dosage must be customized by a physician. Regular monitoring of liver function is recommended during therapy.
- Body Weight
- Below 5 kg
- Dose
- 10-20 mg/kg per day
- Frequency
- Once daily
- Tracking Notes
- Requires strict medical supervision. Dosage must be calculated precisely based on exact weight.
- Body Weight
- 5-7 kg
- Dose
- 50 mg to 140 mg
- Frequency
- Once daily
- Tracking Notes
- Typically administered using a compounded oral liquid suspension for accurate dosing.
- Body Weight
- 8-10 kg
- Dose
- 80 mg to 200 mg
- Frequency
- Once daily
- Tracking Notes
- Administer on an empty stomach. Do not skip doses to prevent bacterial resistance.
- Body Weight
- 11-15 kg
- Dose
- 110 mg to 300 mg
- Frequency
- Once daily
- Tracking Notes
- Adjust dosage as the child's weight changes. Monitor liver enzymes.
- Body Weight
- 16-20 kg
- Dose
- 160 mg to 400 mg
- Frequency
- Once daily
- Tracking Notes
- Ensure complete course of therapy is finished even if the patient feels better.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | 10-20 mg/kg per day | Once daily | Requires strict medical supervision. Dosage must be calculated precisely based on exact weight. |
| 5-7 kg | 50 mg to 140 mg | Once daily | Typically administered using a compounded oral liquid suspension for accurate dosing. |
| 8-10 kg | 80 mg to 200 mg | Once daily | Administer on an empty stomach. Do not skip doses to prevent bacterial resistance. |
| 11-15 kg | 110 mg to 300 mg | Once daily | Adjust dosage as the child's weight changes. Monitor liver enzymes. |
| 16-20 kg | 160 mg to 400 mg | Once daily | Ensure complete course of therapy is finished even if the patient feels better. |
Formulation
Purpose
Used in combination with other antituberculosis drugs for the treatment of all forms of tuberculosis, and for the short-term treatment of asymptomatic carriers of Neisseria meningitidis to eliminate meningococci from the nasopharynx.
Generic Name
RifampinScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.