Risperdal
Risperdal is an atypical antipsychotic agent that works by antagonizing dopamine D2 and serotonin 5-HT2A receptors in the brain, helping to manage symptoms of schizophrenia, bipolar mania, and irritability associated with autism.
Dosage by Body Weight
Dosage must be individualized. Typically initiated at 1 to 2 mg daily in adults, titrated slowly. In pediatric patients with autism, dosing is often initiated at 0.25 mg to 0.5 mg daily based on body weight.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in patients weighing less than 15 kg for autism or in very young pediatric populations.
- Body Weight
- 5-7 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in this weight range.
- Body Weight
- 8-10 kg
- Dose
- Not routinely recommended
- Frequency
- N/A
- Tracking Notes
- Use only if specifically prescribed and monitored by a pediatric specialist.
- Body Weight
- 11-15 kg
- Dose
- 0.25 mg daily
- Frequency
- Once daily or split twice daily
- Tracking Notes
- Starting dose for patients weighing less than 20 kg (for autism indication). Can increase to 0.5 mg/day after 4 days.
- Body Weight
- 16-20 kg
- Dose
- 0.25 mg daily
- Frequency
- Once daily or split twice daily
- Tracking Notes
- Starting dose for patients weighing less than 20 kg. Dose may be increased to 0.5 mg/day after a minimum of 4 days.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | N/A | Safety and efficacy have not been established in patients weighing less than 15 kg for autism or in very young pediatric populations. |
| 5-7 kg | Not recommended | N/A | Safety and efficacy have not been established in this weight range. |
| 8-10 kg | Not routinely recommended | N/A | Use only if specifically prescribed and monitored by a pediatric specialist. |
| 11-15 kg | 0.25 mg daily | Once daily or split twice daily | Starting dose for patients weighing less than 20 kg (for autism indication). Can increase to 0.5 mg/day after 4 days. |
| 16-20 kg | 0.25 mg daily | Once daily or split twice daily | Starting dose for patients weighing less than 20 kg. Dose may be increased to 0.5 mg/day after a minimum of 4 days. |
Formulation
TabletOral SolutionOrally Disintegrating Tablet
Purpose
Treatment of schizophrenia, acute manic or mixed episodes associated with Bipolar I Disorder, and irritability associated with autistic disorder in pediatric patients.
Generic Name
RisperidoneScheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.