Retapamulin
Retapamulin is a semi-synthetic pleuromutilin antibacterial agent. It exerts its therapeutic effect by selectively inhibiting bacterial protein synthesis through binding to a unique site on the 50S subunit of the bacterial ribosome. It is primarily prescribed as a 1% topical ointment for superficial skin infections.
Dosage by Body Weight
Apply a thin layer of retapamulin ointment (1%) to the affected area twice daily for 5 days. The treated area may be covered with a sterile bandage or gauze dressing if necessary.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- Do not use
- Tracking Notes
- Safety and efficacy of retapamulin have not been established in pediatric patients younger than 9 months of age.
- Body Weight
- 5-7 kg
- Dose
- Not routine / Consult physician
- Frequency
- Use only if prescribed
- Tracking Notes
- Retapamulin is indicated only for pediatric patients aged 9 months and older. Most infants in this weight range are under 9 months.
- Body Weight
- 8-10 kg
- Dose
- Apply a thin layer to the affected area
- Frequency
- 2 times daily for 5 days
- Tracking Notes
- Ensure the pediatric patient is at least 9 months of age. Avoid application near the eyes, mouth, or inside the nose.
- Body Weight
- 11-15 kg
- Dose
- Apply a thin layer to the affected area
- Frequency
- 2 times daily for 5 days
- Tracking Notes
- Wash hands thoroughly before and after application. The treated area may be covered with a sterile bandage.
- Body Weight
- 16-20 kg
- Dose
- Apply a thin layer to the affected area
- Frequency
- 2 times daily for 5 days
- Tracking Notes
- For topical dermatological use only. Do not ingest or apply to mucosal surfaces.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | Do not use | Safety and efficacy of retapamulin have not been established in pediatric patients younger than 9 months of age. |
| 5-7 kg | Not routine / Consult physician | Use only if prescribed | Retapamulin is indicated only for pediatric patients aged 9 months and older. Most infants in this weight range are under 9 months. |
| 8-10 kg | Apply a thin layer to the affected area | 2 times daily for 5 days | Ensure the pediatric patient is at least 9 months of age. Avoid application near the eyes, mouth, or inside the nose. |
| 11-15 kg | Apply a thin layer to the affected area | 2 times daily for 5 days | Wash hands thoroughly before and after application. The treated area may be covered with a sterile bandage. |
| 16-20 kg | Apply a thin layer to the affected area | 2 times daily for 5 days | For topical dermatological use only. Do not ingest or apply to mucosal surfaces. |
Formulation
Purpose
Retapamulin is a topical antibiotic used to treat impetigo, a contagious bacterial skin infection, caused by susceptible strains of Staphylococcus aureus (methicillin-susceptible only) or Streptococcus pyogenes in adults and pediatric patients aged 9 months and older.
Generic Name
RetapamulinBranded Drug Names
Retapamulin is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.