Remimazolam
Remimazolam is an ultra-short-acting benzodiazepine sedative-hypnotic. It binds to GABA-A receptors in the central nervous system to produce sedative effects. It is rapidly metabolized by tissue esterases, leading to a quick onset and predictable, fast recovery time.
Dosage by Body Weight
For procedural sedation in adults, the standard initial dose is 5 mg administered intravenously over a 1-minute period. Supplemental doses of 2.5 mg IV over 15 seconds may be given after at least 2 minutes if necessary. It must only be administered by trained healthcare professionals in a monitored setting.
- Body Weight
- Below 5 kg
- Dose
- Not established
- Frequency
- Not applicable
- Tracking Notes
- Safety and effectiveness in pediatric patients have not been established.
- Body Weight
- 5-7 kg
- Dose
- Not established
- Frequency
- Not applicable
- Tracking Notes
- Safety and effectiveness in pediatric patients have not been established.
- Body Weight
- 8-10 kg
- Dose
- Not established
- Frequency
- Not applicable
- Tracking Notes
- Safety and effectiveness in pediatric patients have not been established.
- Body Weight
- 11-15 kg
- Dose
- Not established
- Frequency
- Not applicable
- Tracking Notes
- Safety and effectiveness in pediatric patients have not been established.
- Body Weight
- 16-20 kg
- Dose
- Not established
- Frequency
- Not applicable
- Tracking Notes
- Safety and effectiveness in pediatric patients have not been established.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not established | Not applicable | Safety and effectiveness in pediatric patients have not been established. |
| 5-7 kg | Not established | Not applicable | Safety and effectiveness in pediatric patients have not been established. |
| 8-10 kg | Not established | Not applicable | Safety and effectiveness in pediatric patients have not been established. |
| 11-15 kg | Not established | Not applicable | Safety and effectiveness in pediatric patients have not been established. |
| 16-20 kg | Not established | Not applicable | Safety and effectiveness in pediatric patients have not been established. |
Formulation
Purpose
Induction and maintenance of procedural sedation in adults for procedures lasting 30 minutes or less, and for general anesthesia.
Generic Name
RemimazolamBranded Drug Names
Remimazolam is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.