Rasuvo
Rasuvo is a single-dose subcutaneous auto-injector containing methotrexate, a folate analog metabolic inhibitor. It is designed for once-weekly administration for autoimmune conditions and psoriasis.
Dosage by Body Weight
Rasuvo is administered subcutaneously once weekly. It must NEVER be taken daily, as daily administration can lead to fatal toxicity. For adults with RA, the typical starting dose is 7.5 mg once weekly. For pediatric JIA, dosing is based on body surface area (BSA).
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in patients in this weight range.
- Body Weight
- 5-7 kg
- Dose
- Dose based on BSA
- Frequency
- Once weekly
- Tracking Notes
- Pediatric JIA dosing is calculated by Body Surface Area (typically 10 mg/m² once weekly) rather than weight alone.
- Body Weight
- 8-10 kg
- Dose
- Dose based on BSA
- Frequency
- Once weekly
- Tracking Notes
- Pediatric JIA dosing is calculated by Body Surface Area (typically 10 mg/m² once weekly) rather than weight alone.
- Body Weight
- 11-15 kg
- Dose
- Dose based on BSA
- Frequency
- Once weekly
- Tracking Notes
- Pediatric JIA dosing is calculated by Body Surface Area (typically 10 mg/m² once weekly) rather than weight alone.
- Body Weight
- 16-20 kg
- Dose
- Dose based on BSA
- Frequency
- Once weekly
- Tracking Notes
- Pediatric JIA dosing is calculated by Body Surface Area (typically 10 mg/m² once weekly) rather than weight alone.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | N/A | Safety and efficacy have not been established in patients in this weight range. |
| 5-7 kg | Dose based on BSA | Once weekly | Pediatric JIA dosing is calculated by Body Surface Area (typically 10 mg/m² once weekly) rather than weight alone. |
| 8-10 kg | Dose based on BSA | Once weekly | Pediatric JIA dosing is calculated by Body Surface Area (typically 10 mg/m² once weekly) rather than weight alone. |
| 11-15 kg | Dose based on BSA | Once weekly | Pediatric JIA dosing is calculated by Body Surface Area (typically 10 mg/m² once weekly) rather than weight alone. |
| 16-20 kg | Dose based on BSA | Once weekly | Pediatric JIA dosing is calculated by Body Surface Area (typically 10 mg/m² once weekly) rather than weight alone. |
Formulation
Purpose
Treatment of severe, active rheumatoid arthritis (RA) in adults, polyarticular juvenile idiopathic arthritis (pJIA) in pediatric patients, and control of severe, recalcitrant, disabling psoriasis in adults.
Generic Name
MethotrexateScheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.