Pitressin
Pitressin is a sterile, aqueous solution of synthetic vasopressin (antidiuretic hormone) of the posterior pituitary gland. It possesses pressor and antidiuretic properties, acting on the kidney's renal tubules to facilitate water reabsorption and contracting smooth muscles of the gastrointestinal tract and vascular bed.
Dosage by Body Weight
Must be administered subcutaneously or intramuscularly. For postoperative abdominal distention, the typical adult dose is 5 units (0.25 mL) initially, which may be increased to 10 units (0.5 mL) for subsequent injections given every 3 to 4 hours as needed. For diabetes insipidus, the adult dose is 5 to 10 units (0.25 to 0.5 mL) administered 2 to 3 times daily.
- Body Weight
- Below 5 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Extreme caution required in neonates and infants due to high risk of water intoxication and hyponatremia.
- Body Weight
- 5-7 kg
- Dose
- Highly individualized
- Frequency
- As directed by a specialist
- Tracking Notes
- Dosage must be carefully calculated by a pediatric specialist based on fluid balance and serum electrolytes.
- Body Weight
- 8-10 kg
- Dose
- Highly individualized
- Frequency
- As directed by a specialist
- Tracking Notes
- Requires strict monitoring of urine output, specific gravity, and serum sodium levels.
- Body Weight
- 11-15 kg
- Dose
- Highly individualized
- Frequency
- As directed by a specialist
- Tracking Notes
- Strict fluid restriction is typically necessary to prevent water intoxication.
- Body Weight
- 16-20 kg
- Dose
- Highly individualized
- Frequency
- As directed by a specialist
- Tracking Notes
- Must be administered under close clinical and laboratory supervision.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine | Use only if prescribed | Extreme caution required in neonates and infants due to high risk of water intoxication and hyponatremia. |
| 5-7 kg | Highly individualized | As directed by a specialist | Dosage must be carefully calculated by a pediatric specialist based on fluid balance and serum electrolytes. |
| 8-10 kg | Highly individualized | As directed by a specialist | Requires strict monitoring of urine output, specific gravity, and serum sodium levels. |
| 11-15 kg | Highly individualized | As directed by a specialist | Strict fluid restriction is typically necessary to prevent water intoxication. |
| 16-20 kg | Highly individualized | As directed by a specialist | Must be administered under close clinical and laboratory supervision. |
Formulation
Purpose
Used for the prevention and treatment of postoperative abdominal distention, to dispel gas shadows in abdominal roentgenography, and for the control of central diabetes insipidus.
Generic Name
VasopressinScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.