Peyona
Peyona is a central nervous system stimulant containing caffeine citrate. It is used to treat primary apnea, a condition where premature infants temporarily stop breathing for 20 seconds or more, by stimulating the respiratory center in the brain.
Dosage by Body Weight
Treatment must be initiated under the supervision of a physician experienced in neonatal intensive care. A loading dose of 20 mg/kg body weight is administered via slow intravenous infusion. A maintenance dose of 5 mg/kg body weight is administered orally or intravenously every 24 hours starting 24 hours after the loading dose.
- Body Weight
- Below 5 kg
- Dose
- Loading: 20 mg/kg; Maintenance: 5 mg/kg
- Frequency
- Loading: once; Maintenance: every 24 hours
- Tracking Notes
- Specifically indicated for premature neonates. Doses are calculated based on caffeine citrate salt weight.
- Body Weight
- 5-7 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Apnea of prematurity typically resolves before infants reach this weight. Only use if specifically indicated by a specialist.
- Body Weight
- 8-10 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Not indicated for standard pediatric use in this weight class.
- Body Weight
- 11-15 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Not indicated for standard pediatric use in this weight class.
- Body Weight
- 16-20 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Not indicated for pediatric use in this weight class.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Loading: 20 mg/kg; Maintenance: 5 mg/kg | Loading: once; Maintenance: every 24 hours | Specifically indicated for premature neonates. Doses are calculated based on caffeine citrate salt weight. |
| 5-7 kg | Not routine | Use only if prescribed | Apnea of prematurity typically resolves before infants reach this weight. Only use if specifically indicated by a specialist. |
| 8-10 kg | Not routine | Use only if prescribed | Not indicated for standard pediatric use in this weight class. |
| 11-15 kg | Not routine | Use only if prescribed | Not indicated for standard pediatric use in this weight class. |
| 16-20 kg | Not routine | Use only if prescribed | Not indicated for pediatric use in this weight class. |
Formulation
Purpose
Treatment of primary apnea of premature newborns (premature babies).
Generic Name
Caffeine citrateScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.