Perinorm
Perinorm is an antiemetic and prokinetic medication containing Metoclopramide. It works by blocking dopamine receptors in the brain's chemoreceptor trigger zone to prevent nausea and vomiting, while simultaneously stimulating muscle contractions in the upper digestive tract to speed up gastric emptying.
Dosage by Body Weight
For adults, the typical oral dose is 10 mg taken up to 3 times daily, 30 minutes before meals and at bedtime. Treatment duration should ideally not exceed 5 days to minimize the risk of serious neurological side effects such as tardive dyskinesia.
- Body Weight
- Below 5 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Generally avoided in neonates and infants under 1 year due to a high risk of neurological and extrapyramidal side effects.
- Body Weight
- 5-7 kg
- Dose
- 0.5 mg to 1 mg
- Frequency
- Up to 3 times daily
- Tracking Notes
- Strictly follow pediatric prescription. Give 30 minutes before feeding.
- Body Weight
- 8-10 kg
- Dose
- 1 mg
- Frequency
- Up to 3 times daily
- Tracking Notes
- Monitor closely for muscle twitching, unusual eye movements, or severe drowsiness.
- Body Weight
- 11-15 kg
- Dose
- 1.5 mg
- Frequency
- Up to 3 times daily
- Tracking Notes
- Do not exceed the prescribed dose. Discontinue immediately if spasm or restlessness develops.
- Body Weight
- 16-20 kg
- Dose
- 2 mg
- Frequency
- Up to 3 times daily
- Tracking Notes
- Maintain a minimum interval of 6 hours between doses. Avoid prolonged use beyond 5 days.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine | Use only if prescribed | Generally avoided in neonates and infants under 1 year due to a high risk of neurological and extrapyramidal side effects. |
| 5-7 kg | 0.5 mg to 1 mg | Up to 3 times daily | Strictly follow pediatric prescription. Give 30 minutes before feeding. |
| 8-10 kg | 1 mg | Up to 3 times daily | Monitor closely for muscle twitching, unusual eye movements, or severe drowsiness. |
| 11-15 kg | 1.5 mg | Up to 3 times daily | Do not exceed the prescribed dose. Discontinue immediately if spasm or restlessness develops. |
| 16-20 kg | 2 mg | Up to 3 times daily | Maintain a minimum interval of 6 hours between doses. Avoid prolonged use beyond 5 days. |
Formulation
Purpose
Used to treat and prevent nausea, vomiting, indigestion, heartburn, and diabetic gastroparesis (delayed stomach emptying).
Generic Name
MetoclopramideScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.