Norpramin

Norpramin is a tricyclic antidepressant (TCA) that works by increasing the levels of certain natural chemicals (such as norepinephrine) in the brain to help restore mental balance and improve mood.

Dosage by Body Weight

Adults: Typically 100 mg to 200 mg daily, often initiated at 25-50 mg/day and gradually titrated upward. Adolescent and Geriatric patients: 25 mg to 100 mg daily. Safe pediatric dosing for patients under 12 years of age is not established.

  1. Body Weight
    Below 5 kg
    Dose
    Contraindicated
    Frequency
    N/A
    Tracking Notes
    Not recommended for infants or young children. Safety and efficacy are not established.
  2. Body Weight
    5-7 kg
    Dose
    Contraindicated
    Frequency
    N/A
    Tracking Notes
    Not recommended for infants or young children. Safety and efficacy are not established.
  3. Body Weight
    8-10 kg
    Dose
    Contraindicated
    Frequency
    N/A
    Tracking Notes
    Not recommended for young children. Safety and efficacy are not established.
  4. Body Weight
    11-15 kg
    Dose
    Contraindicated
    Frequency
    N/A
    Tracking Notes
    Safety and efficacy in pediatric patients under 12 years of age have not been established.
  5. Body Weight
    16-20 kg
    Dose
    Contraindicated
    Frequency
    N/A
    Tracking Notes
    Safety and efficacy in pediatric patients under 12 years of age have not been established.

Formulation

Tablet

Purpose

Primarily used for the treatment of depression. It may also be used off-label for attention deficit hyperactivity disorder (ADHD), neuropathic pain, and panic disorder.

Generic Name

Desipramine hydrochloride

Scheduled Drug

No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.

Alternatives

Disclaimer: This information is for educational purposes only. WHO references and weight bands are simplified for tracking and must not replace medical advice. Always consult with a healthcare professional before starting or changing any medication.