Percorten-V
Percorten-V (desoxycorticosterone pivalate) is a mineralocorticoid hormone clinically proven for the treatment of canine Addison's disease. It is administered via intramuscular or subcutaneous injection and must be used under veterinary supervision alongside appropriate glucocorticoid replacement therapy.
Dosage by Body Weight
The standard starting dose is 2.2 mg/kg (1 mg/lb) of body weight, administered subcutaneously or intramuscularly approximately every 25 to 30 days. Dosage and treatment intervals must be individualized based on clinical response and regular monitoring of serum sodium and potassium levels.
- Body Weight
- Below 5 kg
- Dose
- Up to 11 mg (approx. 0.44 mL or less)
- Frequency
- Every 25 to 30 days
- Tracking Notes
- Calculate exact dose at 2.2 mg/kg. Under veterinary supervision, adjust dose based on sodium/potassium ratio.
- Body Weight
- 5-7 kg
- Dose
- 11 mg - 15.4 mg (approx. 0.44 mL - 0.62 mL)
- Frequency
- Every 25 to 30 days
- Tracking Notes
- Monitor sodium and potassium levels at day 14 and day 25 post-injection to determine dose efficacy.
- Body Weight
- 8-10 kg
- Dose
- 17.6 mg - 22 mg (approx. 0.70 mL - 0.88 mL)
- Frequency
- Every 25 to 30 days
- Tracking Notes
- Shake the vial vigorously to ensure uniform suspension before drawing the dose.
- Body Weight
- 11-15 kg
- Dose
- 24.2 mg - 33 mg (approx. 0.97 mL - 1.32 mL)
- Frequency
- Every 25 to 30 days
- Tracking Notes
- Doses should be adjusted downward if signs of mineralocorticoid excess (e.g., polyuria/polydipsia) are observed.
- Body Weight
- 16-20 kg
- Dose
- 35.2 mg - 44 mg (approx. 1.41 mL - 1.76 mL)
- Frequency
- Every 25 to 30 days
- Tracking Notes
- Most dogs also require concurrent daily glucocorticoid therapy (like prednisone).
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Up to 11 mg (approx. 0.44 mL or less) | Every 25 to 30 days | Calculate exact dose at 2.2 mg/kg. Under veterinary supervision, adjust dose based on sodium/potassium ratio. |
| 5-7 kg | 11 mg - 15.4 mg (approx. 0.44 mL - 0.62 mL) | Every 25 to 30 days | Monitor sodium and potassium levels at day 14 and day 25 post-injection to determine dose efficacy. |
| 8-10 kg | 17.6 mg - 22 mg (approx. 0.70 mL - 0.88 mL) | Every 25 to 30 days | Shake the vial vigorously to ensure uniform suspension before drawing the dose. |
| 11-15 kg | 24.2 mg - 33 mg (approx. 0.97 mL - 1.32 mL) | Every 25 to 30 days | Doses should be adjusted downward if signs of mineralocorticoid excess (e.g., polyuria/polydipsia) are observed. |
| 16-20 kg | 35.2 mg - 44 mg (approx. 1.41 mL - 1.76 mL) | Every 25 to 30 days | Most dogs also require concurrent daily glucocorticoid therapy (like prednisone). |
Formulation
Purpose
Percorten-V is used as a replacement therapy for the mineralocorticoid deficit in dogs with primary hypoadrenocorticism (Addison's disease). It helps regulate electrolyte balance by promoting sodium retention and potassium excretion.
Generic Name
Desoxycorticosterone pivalate (DOCP)Scheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.