Panimun
Panimun contains Cyclosporine, which is an immunosuppressant medication. It works by dampening the body's natural defense system to help it accept a transplanted organ, or to control severe autoimmune conditions like rheumatoid arthritis and psoriasis.
Dosage by Body Weight
Dosage is highly individualized and must be adjusted based on clinical response, blood trough levels, and tolerability. Must be taken at the same time daily, with or without food. Avoid grapefruit juice.
- Body Weight
- Below 5 kg
- Dose
- Specialist calculation (Typically 2 to 15 mg/kg/day)
- Frequency
- Divided into 2 doses daily
- Tracking Notes
- Highly critical pediatric dosing. Requires strict specialist monitoring of blood levels.
- Body Weight
- 5-7 kg
- Dose
- Based on 2-15 mg/kg/day (approx. 10-105 mg daily)
- Frequency
- Divided into 2 doses daily
- Tracking Notes
- Monitor kidney function and blood pressure regularly.
- Body Weight
- 8-10 kg
- Dose
- Based on 2-15 mg/kg/day (approx. 16-150 mg daily)
- Frequency
- Divided into 2 doses daily
- Tracking Notes
- Dose varies significantly based on whether used for transplant or autoimmune disease.
- Body Weight
- 11-15 kg
- Dose
- Based on 2-15 mg/kg/day (approx. 22-225 mg daily)
- Frequency
- Divided into 2 doses daily
- Tracking Notes
- Regular blood trough concentration monitoring is essential to avoid toxicity.
- Body Weight
- 16-20 kg
- Dose
- Based on 2-15 mg/kg/day (approx. 32-300 mg daily)
- Frequency
- Divided into 2 doses daily
- Tracking Notes
- Maintain consistent brand/manufacturer usage; do not switch formulations without consulting a physician.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Specialist calculation (Typically 2 to 15 mg/kg/day) | Divided into 2 doses daily | Highly critical pediatric dosing. Requires strict specialist monitoring of blood levels. |
| 5-7 kg | Based on 2-15 mg/kg/day (approx. 10-105 mg daily) | Divided into 2 doses daily | Monitor kidney function and blood pressure regularly. |
| 8-10 kg | Based on 2-15 mg/kg/day (approx. 16-150 mg daily) | Divided into 2 doses daily | Dose varies significantly based on whether used for transplant or autoimmune disease. |
| 11-15 kg | Based on 2-15 mg/kg/day (approx. 22-225 mg daily) | Divided into 2 doses daily | Regular blood trough concentration monitoring is essential to avoid toxicity. |
| 16-20 kg | Based on 2-15 mg/kg/day (approx. 32-300 mg daily) | Divided into 2 doses daily | Maintain consistent brand/manufacturer usage; do not switch formulations without consulting a physician. |
Formulation
Purpose
Used to prevent organ rejection in transplant recipients (kidney, liver, heart) and to treat severe rheumatoid arthritis and severe psoriasis.
Generic Name
CyclosporineScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.