Nitronal
Nitronal is a sterile, concentrated solution of glyceryl trinitrate (nitroglycerin) intended for intravenous administration after dilution. It acts as a potent vasodilator, primarily affecting venous vessels, which reduces cardiac preload and afterload, decreasing myocardial oxygen demand.
Dosage by Body Weight
Nitronal must be administered via intravenous infusion only, diluted in a compatible fluid, and carefully titrated based on the patient's individual clinical response, blood pressure, and heart rate. Typically started at a rate of 10 to 200 micrograms/minute.
- Body Weight
- Below 5 kg
- Dose
- Requires specialist ICU titration
- Frequency
- Continuous infusion
- Tracking Notes
- Safety and efficacy in pediatric patients have not been established; use only under expert neonatal/pediatric intensive care supervision.
- Body Weight
- 5-7 kg
- Dose
- Requires specialist ICU titration
- Frequency
- Continuous infusion
- Tracking Notes
- Dosing must be strictly supervised in an ICU setting, titrated carefully to hemodynamics.
- Body Weight
- 8-10 kg
- Dose
- Requires specialist ICU titration
- Frequency
- Continuous infusion
- Tracking Notes
- Dosage is titrated based on blood pressure and heart rate response.
- Body Weight
- 11-15 kg
- Dose
- Requires specialist ICU titration
- Frequency
- Continuous infusion
- Tracking Notes
- Continuous hemodynamic monitoring is mandatory during administration.
- Body Weight
- 16-20 kg
- Dose
- Requires specialist ICU titration
- Frequency
- Continuous infusion
- Tracking Notes
- Adjust infusion rate gradually to achieve the desired therapeutic effect without severe hypotension.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Requires specialist ICU titration | Continuous infusion | Safety and efficacy in pediatric patients have not been established; use only under expert neonatal/pediatric intensive care supervision. |
| 5-7 kg | Requires specialist ICU titration | Continuous infusion | Dosing must be strictly supervised in an ICU setting, titrated carefully to hemodynamics. |
| 8-10 kg | Requires specialist ICU titration | Continuous infusion | Dosage is titrated based on blood pressure and heart rate response. |
| 11-15 kg | Requires specialist ICU titration | Continuous infusion | Continuous hemodynamic monitoring is mandatory during administration. |
| 16-20 kg | Requires specialist ICU titration | Continuous infusion | Adjust infusion rate gradually to achieve the desired therapeutic effect without severe hypotension. |
Formulation
Purpose
Used for the treatment of severe angina pectoris, unstable angina, acute myocardial infarction, acute left ventricular failure, and control of hypertensive episodes during cardiac surgery.
Generic Name
Glyceryl TrinitrateScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.