Naloxone

An opioid antagonist that rapidly binds to opioid receptors, blocking the effects of drugs like morphine, heroin, or fentanyl.

Dosage by Body Weight

In a pediatric emergency (accidental ingestion), 0.1 mg/kg is given. Nasal spray is fixed-dose (4mg) and safe for use in all ages.

  1. Body Weight
    Any weight
    Dose
    4 mg (Nasal) or 0.1 mg/kg (IM)
    Frequency
    Once (Repeat every 2-3 mins if no response)
    Tracking Notes
    Always call emergency services immediately.

Formulation

Nasal SprayInjection

Purpose

Emergency reversal of opioid overdose.

Generic Name

Naloxone Hydrochloride

Branded Drug Names

Naloxone is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:

Scheduled Drug

Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.

Alternatives

Safety Advice

Alcohol

CAUTION

Naloxone: Alcohol may increase dizziness, stomach upset, dehydration, or other side effects. Avoid or limit alcohol and follow medical advice.

Pregnancy

SAFE IF PRESCRIBED

Naloxone: Use during pregnancy only if prescribed after a healthcare provider weighs the benefits and risks.

Breast Feeding

SAFE IF PRESCRIBED

Naloxone: Use while breastfeeding only with healthcare provider guidance, especially for repeated or long-term treatment.

Driving

CAUTION

Naloxone: This medicine may cause dizziness, drowsiness, weakness, or blurred vision in some people. Avoid driving if affected.

Liver

CAUTION

Naloxone: Use with caution in liver disease and consult your healthcare provider if you have abnormal liver tests or jaundice.

Kidney

CAUTION

Naloxone: Use with caution in kidney disease because dose adjustment or monitoring may be needed for some patients.

Disclaimer: This information is for educational purposes only. WHO references and weight bands are simplified for tracking and must not replace medical advice. Always consult with a healthcare professional before starting or changing any medication.