Kloxxado
Kloxxado is a rapid-acting opioid antagonist containing 8 mg of naloxone hydrochloride per spray, designed to reverse life-threatening respiratory depression caused by an opioid overdose.
Dosage by Body Weight
Administer 1 spray (8 mg) into one nostril. Call 911 immediately. If the patient does not respond or relapses, administer an additional spray every 2 to 3 minutes using a new device in alternating nostrils.
- Body Weight
- Below 5 kg
- Dose
- 8 mg (1 spray)
- Frequency
- Single dose, repeat every 2-3 minutes as needed
- Tracking Notes
- Emergency reversal. Standard dose is administered regardless of weight due to the life-threatening nature of opioid overdose.
- Body Weight
- 5-7 kg
- Dose
- 8 mg (1 spray)
- Frequency
- Single dose, repeat every 2-3 minutes as needed
- Tracking Notes
- Emergency reversal. Standard dose is administered regardless of weight.
- Body Weight
- 8-10 kg
- Dose
- 8 mg (1 spray)
- Frequency
- Single dose, repeat every 2-3 minutes as needed
- Tracking Notes
- Emergency reversal. Standard dose is administered regardless of weight.
- Body Weight
- 11-15 kg
- Dose
- 8 mg (1 spray)
- Frequency
- Single dose, repeat every 2-3 minutes as needed
- Tracking Notes
- Emergency reversal. Standard dose is administered regardless of weight.
- Body Weight
- 16-20 kg
- Dose
- 8 mg (1 spray)
- Frequency
- Single dose, repeat every 2-3 minutes as needed
- Tracking Notes
- Emergency reversal. Standard dose is administered regardless of weight.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | 8 mg (1 spray) | Single dose, repeat every 2-3 minutes as needed | Emergency reversal. Standard dose is administered regardless of weight due to the life-threatening nature of opioid overdose. |
| 5-7 kg | 8 mg (1 spray) | Single dose, repeat every 2-3 minutes as needed | Emergency reversal. Standard dose is administered regardless of weight. |
| 8-10 kg | 8 mg (1 spray) | Single dose, repeat every 2-3 minutes as needed | Emergency reversal. Standard dose is administered regardless of weight. |
| 11-15 kg | 8 mg (1 spray) | Single dose, repeat every 2-3 minutes as needed | Emergency reversal. Standard dose is administered regardless of weight. |
| 16-20 kg | 8 mg (1 spray) | Single dose, repeat every 2-3 minutes as needed | Emergency reversal. Standard dose is administered regardless of weight. |
Formulation
Nasal Spray
Purpose
Emergency treatment of known or suspected opioid overdose, manifested by respiratory and/or central nervous system depression.
Generic Name
Naloxone hydrochlorideScheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.