Mesna
A cytoprotective agent that detoxifies harmful metabolites of chemotherapy drugs in the bladder.
Dosage by Body Weight
Dose is usually 20% of the total chemotherapy dose, given at the time of chemo and then 4 and 8 hours later.
- Body Weight
- Oncology patients
- Dose
- Calculated based on Chemo dose
- Frequency
- Specific schedule
- Tracking Notes
- Maintaining high fluid intake is also essential.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Oncology patients | Calculated based on Chemo dose | Specific schedule | Maintaining high fluid intake is also essential. |
Formulation
Purpose
Prevention of hemorrhagic cystitis (bladder bleeding) caused by cyclophosphamide or ifosfamide chemotherapy.
Generic Name
MesnaBranded Drug Names
Mesna is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
CAUTIONMesna: Alcohol can increase liver strain, stomach irritation, or immune-related complications. Avoid alcohol unless your specialist allows it.
Pregnancy
CAUTIONMesna: Use in pregnancy only under specialist advice because immune, cancer, or transplant treatment requires careful risk assessment.
Breast Feeding
CAUTIONMesna: Breastfeeding may not be recommended with some immunosuppressive or chemotherapy medicines. Follow specialist advice.
Driving
CAUTIONMesna: May cause dizziness, fatigue, nausea, or weakness. Avoid driving if affected.
Liver
CAUTIONMesna: Can affect liver function and usually requires regular blood tests. Use only with specialist monitoring.
Kidney
CAUTIONMesna: Kidney function may need close monitoring, particularly with calcineurin inhibitors or high-risk regimens.