Lokmal Suspension
Lokmal Suspension is a fixed-dose combination antimalarial medication containing Artemether and Lumefantrine. It is formulated as a dry powder for reconstitution into an oral suspension, primarily used for treating Plasmodium falciparum malaria in pediatric patients. Artemether acts quickly to reduce parasite biomass, while Lumefantrine clears residual parasites.
Dosage by Body Weight
The standard regimen consists of 6 doses administered over 3 days. The first dose is given at diagnosis (Hour 0), followed by the second dose 8 hours later. For the next 2 days, doses are given twice daily (morning and evening). It must be administered with a fatty meal, milk, or breast milk to ensure adequate absorption.
- Body Weight
- Below 5 kg
- Dose
- Safety and efficacy not established
- Frequency
- Not recommended
- Tracking Notes
- Consult a physician or pediatrician before use.
- Body Weight
- 5-7 kg
- Dose
- 5 mL (Artemether 20 mg / Lumefantrine 120 mg)
- Frequency
- 6 doses over 3 days (Hour 0, Hour 8, then twice daily for Days 2 & 3)
- Tracking Notes
- Always give with milk or fatty food.
- Body Weight
- 8-10 kg
- Dose
- 5 mL (Artemether 20 mg / Lumefantrine 120 mg)
- Frequency
- 6 doses over 3 days (Hour 0, Hour 8, then twice daily for Days 2 & 3)
- Tracking Notes
- Ensure child finishes the full 3-day course even if they feel better.
- Body Weight
- 11-15 kg
- Dose
- 5 mL (Artemether 20 mg / Lumefantrine 120 mg)
- Frequency
- 6 doses over 3 days (Hour 0, Hour 8, then twice daily for Days 2 & 3)
- Tracking Notes
- If the child vomits within 1 hour of administration, repeat the dose.
- Body Weight
- 16-20 kg
- Dose
- 10 mL (Artemether 40 mg / Lumefantrine 240 mg)
- Frequency
- 6 doses over 3 days (Hour 0, Hour 8, then twice daily for Days 2 & 3)
- Tracking Notes
- For children in the 15-25 kg weight range. Administer with food.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Safety and efficacy not established | Not recommended | Consult a physician or pediatrician before use. |
| 5-7 kg | 5 mL (Artemether 20 mg / Lumefantrine 120 mg) | 6 doses over 3 days (Hour 0, Hour 8, then twice daily for Days 2 & 3) | Always give with milk or fatty food. |
| 8-10 kg | 5 mL (Artemether 20 mg / Lumefantrine 120 mg) | 6 doses over 3 days (Hour 0, Hour 8, then twice daily for Days 2 & 3) | Ensure child finishes the full 3-day course even if they feel better. |
| 11-15 kg | 5 mL (Artemether 20 mg / Lumefantrine 120 mg) | 6 doses over 3 days (Hour 0, Hour 8, then twice daily for Days 2 & 3) | If the child vomits within 1 hour of administration, repeat the dose. |
| 16-20 kg | 10 mL (Artemether 40 mg / Lumefantrine 240 mg) | 6 doses over 3 days (Hour 0, Hour 8, then twice daily for Days 2 & 3) | For children in the 15-25 kg weight range. Administer with food. |
Formulation
Purpose
Treatment of acute, uncomplicated malaria infections caused by Plasmodium falciparum in infants and children.
Generic Name
Artemether + LumefantrineScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.