Liquaemin
Liquaemin is a brand name for heparin sodium, an anticoagulant (blood thinner) that prevents the formation of blood clots. It works by activating antithrombin III, which blocks the action of clotting factors like thrombin. It is administered via intravenous or subcutaneous injection.
Dosage by Body Weight
Dosage must be strictly individualized based on the patient's coagulation test results (such as activated partial thromboplastin time, aPTT). It is typically administered in a clinical setting as a continuous intravenous infusion or intermittent subcutaneous injection.
- Body Weight
- Below 5 kg
- Dose
- 50 to 100 units/kg
- Frequency
- Every 4 to 6 hours or as a continuous IV infusion
- Tracking Notes
- Requires strict clinical monitoring and dosage titration based on aPTT levels.
- Body Weight
- 5-7 kg
- Dose
- 50 to 100 units/kg
- Frequency
- Every 4 to 6 hours or as a continuous IV infusion
- Tracking Notes
- Adjust dosage to maintain therapeutic aPTT ranges.
- Body Weight
- 8-10 kg
- Dose
- 50 to 100 units/kg
- Frequency
- Every 4 to 6 hours or as a continuous IV infusion
- Tracking Notes
- Monitor closely for bleeding risks and platelet counts.
- Body Weight
- 11-15 kg
- Dose
- 50 to 100 units/kg
- Frequency
- Every 4 to 6 hours or as a continuous IV infusion
- Tracking Notes
- Infusion rate must be managed via an automated infusion pump.
- Body Weight
- 16-20 kg
- Dose
- 50 to 100 units/kg
- Frequency
- Every 4 to 6 hours or as a continuous IV infusion
- Tracking Notes
- Coagulation profiles must be performed prior to and during therapy.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | 50 to 100 units/kg | Every 4 to 6 hours or as a continuous IV infusion | Requires strict clinical monitoring and dosage titration based on aPTT levels. |
| 5-7 kg | 50 to 100 units/kg | Every 4 to 6 hours or as a continuous IV infusion | Adjust dosage to maintain therapeutic aPTT ranges. |
| 8-10 kg | 50 to 100 units/kg | Every 4 to 6 hours or as a continuous IV infusion | Monitor closely for bleeding risks and platelet counts. |
| 11-15 kg | 50 to 100 units/kg | Every 4 to 6 hours or as a continuous IV infusion | Infusion rate must be managed via an automated infusion pump. |
| 16-20 kg | 50 to 100 units/kg | Every 4 to 6 hours or as a continuous IV infusion | Coagulation profiles must be performed prior to and during therapy. |
Formulation
Purpose
Anticoagulant therapy to prevent and treat blood clots (such as deep vein thrombosis and pulmonary embolism) and to prevent clotting during heart surgery and dialysis.
Generic Name
Heparin SodiumScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.