Lipochol
Lipochol contains Ursodeoxycholic Acid, a naturally occurring bile acid that helps reduce cholesterol secretion from the liver and slowly dissolves cholesterol-based gallstones. It is also used to improve liver function in patients suffering from primary biliary cholangitis.
Dosage by Body Weight
Dosage is highly individualized based on body weight and the condition being treated. The typical adult dose for gallstone dissolution is 8-10 mg/kg/day, taken in two divided doses or as a single dose at bedtime. For primary biliary cholangitis, the standard dose is 13-15 mg/kg/day in two to four divided doses. It should be taken with food.
- Body Weight
- Below 5 kg
- Dose
- 50 mg to 75 mg daily
- Frequency
- Divided into 2 doses
- Tracking Notes
- Safety and dosing must be strictly supervised by a specialist. Liquid formulations or compounded suspensions are typically required.
- Body Weight
- 5-7 kg
- Dose
- 75 mg to 100 mg daily
- Frequency
- Divided into 2 doses
- Tracking Notes
- Administer with milk or food. Use a compounded oral liquid for precise dosing.
- Body Weight
- 8-10 kg
- Dose
- 120 mg to 150 mg daily
- Frequency
- Divided into 2 doses
- Tracking Notes
- Dose calculated at approximately 15 mg/kg/day for biliary indications.
- Body Weight
- 11-15 kg
- Dose
- 165 mg to 225 mg daily
- Frequency
- Divided into 2 doses
- Tracking Notes
- Regular monitoring of liver enzymes is recommended during therapy.
- Body Weight
- 16-20 kg
- Dose
- 240 mg to 300 mg daily
- Frequency
- Divided into 2 doses
- Tracking Notes
- One 250mg capsule may be administered daily if the child is able to swallow capsules whole.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | 50 mg to 75 mg daily | Divided into 2 doses | Safety and dosing must be strictly supervised by a specialist. Liquid formulations or compounded suspensions are typically required. |
| 5-7 kg | 75 mg to 100 mg daily | Divided into 2 doses | Administer with milk or food. Use a compounded oral liquid for precise dosing. |
| 8-10 kg | 120 mg to 150 mg daily | Divided into 2 doses | Dose calculated at approximately 15 mg/kg/day for biliary indications. |
| 11-15 kg | 165 mg to 225 mg daily | Divided into 2 doses | Regular monitoring of liver enzymes is recommended during therapy. |
| 16-20 kg | 240 mg to 300 mg daily | Divided into 2 doses | One 250mg capsule may be administered daily if the child is able to swallow capsules whole. |
Formulation
Purpose
Used for the dissolution of cholesterol-rich gallstones in patients with a functioning gallbladder, and for the treatment of primary biliary cholangitis (PBC).
Generic Name
Ursodeoxycholic AcidScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.