Doxolin
Doxolin contains Doxofylline, a methylxanthine bronchodilator. It works by relaxing the smooth muscles of the bronchial airways, thereby decreasing airway resistance and facilitating easier breathing. Unlike older xanthines, it has a lower affinity for adenosine receptors, resulting in fewer cardiac and central nervous system side effects.
Dosage by Body Weight
Adults typically take 400 mg once daily, preferably in the evening, though some patients may require 400 mg twice daily. Pediatric dosage is calculated based on body weight (typically 12-18 mg/kg per day divided into two doses) and should only be administered under strict medical supervision.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- Do not use
- Tracking Notes
- Safety and efficacy have not been established for infants.
- Body Weight
- 5-7 kg
- Dose
- Not recommended
- Frequency
- Do not use
- Tracking Notes
- Safety and efficacy have not been established in this weight range.
- Body Weight
- 8-10 kg
- Dose
- Not routinely recommended
- Frequency
- Consult physician
- Tracking Notes
- Use only if specifically prescribed by a pediatrician using liquid formulations.
- Body Weight
- 11-15 kg
- Dose
- 60 mg to 90 mg (3 ml to 4.5 ml of 100mg/5ml syrup)
- Frequency
- Twice daily
- Tracking Notes
- Calculated at approximately 12 mg/kg/day. Use with caution under expert supervision.
- Body Weight
- 16-20 kg
- Dose
- 100 mg to 120 mg (5 ml to 6 ml of 100mg/5ml syrup)
- Frequency
- Twice daily
- Tracking Notes
- Calculated at approximately 12 mg/kg/day. Monitor closely for side effects like headache or nausea.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | Do not use | Safety and efficacy have not been established for infants. |
| 5-7 kg | Not recommended | Do not use | Safety and efficacy have not been established in this weight range. |
| 8-10 kg | Not routinely recommended | Consult physician | Use only if specifically prescribed by a pediatrician using liquid formulations. |
| 11-15 kg | 60 mg to 90 mg (3 ml to 4.5 ml of 100mg/5ml syrup) | Twice daily | Calculated at approximately 12 mg/kg/day. Use with caution under expert supervision. |
| 16-20 kg | 100 mg to 120 mg (5 ml to 6 ml of 100mg/5ml syrup) | Twice daily | Calculated at approximately 12 mg/kg/day. Monitor closely for side effects like headache or nausea. |
Formulation
Purpose
Used for the treatment, control, and prevention of asthma, chronic obstructive pulmonary disease (COPD), and other respiratory conditions involving bronchospasm.
Generic Name
DoxofyllineScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.