Cyclosporine
Inhibits calcineurin, preventing T-cell activation. It revolutionized transplant medicine but requires strict blood level monitoring.
Dosage by Body Weight
Pediatric dose: 5–10 mg/kg/day divided into two doses. Monitor kidney function and blood pressure.
- Body Weight
- 15-25 kg
- Dose
- 50 mg to 100 mg
- Frequency
- Twice daily
- Tracking Notes
- Mix oral solution in glass (not plastic) with chocolate milk or orange juice.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 15-25 kg | 50 mg to 100 mg | Twice daily | Mix oral solution in glass (not plastic) with chocolate milk or orange juice. |
Formulation
Purpose
Immunosuppressant for organ transplant and severe steroid-resistant Nephrotic Syndrome.
Generic Name
Cyclosporine ModifiedBranded Drug Names
Cyclosporine is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
CAUTIONCyclosporine: Alcohol can increase liver strain, stomach irritation, or immune-related complications. Avoid alcohol unless your specialist allows it.
Pregnancy
CAUTIONCyclosporine: Use in pregnancy only under specialist advice because immune, cancer, or transplant treatment requires careful risk assessment.
Breast Feeding
CAUTIONCyclosporine: Breastfeeding may not be recommended with some immunosuppressive or chemotherapy medicines. Follow specialist advice.
Driving
CAUTIONCyclosporine: May cause dizziness, fatigue, nausea, or weakness. Avoid driving if affected.
Liver
CAUTIONCyclosporine: Can affect liver function and usually requires regular blood tests. Use only with specialist monitoring.
Kidney
CAUTIONCyclosporine: Kidney function may need close monitoring, particularly with calcineurin inhibitors or high-risk regimens.