Chloral Hydrate

One of the oldest sedatives. It acts on the CNS to produce sleep without affecting the respiratory system significantly at standard doses.

Dosage by Body Weight

Dose for sedation: 25-50 mg/kg. Must be administered under medical supervision in a clinical setting.

  1. Body Weight
    10-20 kg
    Dose
    250 mg to 1000 mg
    Frequency
    Single dose (Pre-procedure)
    Tracking Notes
    Bitter taste; mix with juice or syrup. Monitor oxygen levels.

Formulation

Oral Solution

Purpose

Short-term sedative used for diagnostic procedures (like MRI or EEG) in children.

Generic Name

Chloral Hydrate

Branded Drug Names

Chloral Hydrate is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:

Scheduled Drug

Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.

Alternatives

Safety Advice

Alcohol

UNSAFE

Chloral Hydrate: Alcohol can worsen drowsiness, mood changes, impaired judgment, or heart rhythm effects. Avoid alcohol unless your prescriber confirms it is safe.

Pregnancy

CAUTION

Chloral Hydrate: Use in pregnancy only when prescribed after weighing mental health benefits and medicine-specific risks.

Breast Feeding

CAUTION

Chloral Hydrate: May pass into breast milk. Use while breastfeeding only with specialist guidance and infant monitoring.

Driving

CAUTION

Chloral Hydrate: May cause sleepiness, dizziness, slowed reaction time, or concentration changes. Avoid driving if affected.

Liver

CAUTION

Chloral Hydrate: Use caution in liver disease because several psychiatric or sedating medicines are processed by the liver.

Kidney

CAUTION

Chloral Hydrate: Kidney disease may require monitoring or dose adjustment for some medicines in this group.

Disclaimer: This information is for educational purposes only. WHO references and weight bands are simplified for tracking and must not replace medical advice. Always consult with a healthcare professional before starting or changing any medication.