Cefotaxime

A broad-spectrum antibiotic used primarily in hospital settings. Unlike ceftriaxone, it is safe for use in neonates with jaundice.

Dosage by Body Weight

Pediatric dose: 100-150 mg/kg/day divided into 3-4 doses. For meningitis: 200 mg/kg/day.

  1. Body Weight
    3-5 kg (Newborn)
    Dose
    150 mg to 250 mg
    Frequency
    Every 8 to 12 hours
    Tracking Notes
    Dose and frequency depend on the age (days) of the newborn.
  2. Body Weight
    10-15 kg
    Dose
    500 mg
    Frequency
    Every 8 hours
    Tracking Notes
    Administer via IV or deep IM injection.

Formulation

Injection (Vial)

Purpose

Third-generation cephalosporin antibiotic for serious infections like meningitis and neonatal sepsis.

Generic Name

Cefotaxime Sodium

Branded Drug Names

Cefotaxime is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:

Scheduled Drug

Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.

Alternatives

Safety Advice

Alcohol

CAUTION

Cefotaxime: Alcohol may worsen infection-related dehydration, dizziness, or stomach upset. Avoid or limit alcohol during antibiotic treatment.

Pregnancy

SAFE IF PRESCRIBED

Cefotaxime: Use during pregnancy only when prescribed for a bacterial infection; the prescriber will choose the safest suitable antibiotic.

Breast Feeding

SAFE IF PRESCRIBED

Cefotaxime: Many antibiotics are compatible with breastfeeding when prescribed, but monitor the infant for diarrhea, rash, or thrush.

Driving

SAFE

Cefotaxime: Usually does not affect driving, but dizziness, weakness, or illness symptoms can occur. Avoid driving if affected.

Liver

CAUTION

Cefotaxime: Use caution in liver disease or if jaundice, dark urine, or severe fatigue occurs during treatment.

Kidney

CAUTION

Cefotaxime: Some antibiotics require dose adjustment or monitoring in kidney disease. Use exactly as prescribed.

Disclaimer: This information is for educational purposes only. WHO references and weight bands are simplified for tracking and must not replace medical advice. Always consult with a healthcare professional before starting or changing any medication.