Atovaquone + Proguanil

A highly effective combination for P. falciparum. The pediatric version (62.5mg/25mg) is designed for easier dosing in children.

Dosage by Body Weight

Prophylaxis: Start 1-2 days before travel and continue for 7 days after. Must be taken with food or a milky drink.

Body Weight
11-20 kg
Dose
1 pediatric tablet
Frequency
Once daily
Tracking Notes
Take at the same time each day with food.
Body Weight
21-30 kg
Dose
2 pediatric tablets
Frequency
Once daily
Tracking Notes
If vomiting occurs within 1 hour, repeat the dose.

Weight-based dosage tracking table for Atovaquone + Proguanil, including body weight, dose, frequency, and tracking notes.
Body Weight	Dose	Frequency	Tracking Notes
11-20 kg	1 pediatric tablet	Once daily	Take at the same time each day with food.
21-30 kg	2 pediatric tablets	Once daily	If vomiting occurs within 1 hour, repeat the dose.

Formulation

Pediatric TabletTablet

Purpose

Prophylaxis and treatment of malaria.

Generic Name

Atovaquone / Proguanil

Branded Drug Names

Atovaquone + Proguanil is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:

Scheduled Drug

Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.

Alternatives

Mefloquine Chloroquine

Safety Advice

Alcohol

CAUTION

Atovaquone + Proguanil: Alcohol may increase dizziness, stomach upset, dehydration, or other side effects. Avoid or limit alcohol and follow medical advice.

Pregnancy

SAFE IF PRESCRIBED

Atovaquone + Proguanil: Use during pregnancy only if prescribed after a healthcare provider weighs the benefits and risks.

Breast Feeding

SAFE IF PRESCRIBED

Atovaquone + Proguanil: Use while breastfeeding only with healthcare provider guidance, especially for repeated or long-term treatment.

Driving

CAUTION

Atovaquone + Proguanil: This medicine may cause dizziness, drowsiness, weakness, or blurred vision in some people. Avoid driving if affected.

Liver

CAUTION

Atovaquone + Proguanil: Use with caution in liver disease and consult your healthcare provider if you have abnormal liver tests or jaundice.

Kidney

CAUTION

Atovaquone + Proguanil: Use with caution in kidney disease because dose adjustment or monitoring may be needed for some patients.