Apovent
Apovent is an anticholinergic bronchodilator containing ipratropium bromide. It works by blocking muscarinic cholinergic receptors in the smooth muscle of the lungs, preventing bronchoconstriction and allowing the airways to dilate, which significantly improves airflow and eases breathing difficulties.
Dosage by Body Weight
Administered via inhalation using a nebulizer or a metered-dose inhaler. Dosage must be individualized. In acute asthma cases, it is frequently co-administered with an inhaled short-acting beta-agonist like salbutamol. Use strictly as directed by a physician.
- Body Weight
- Below 5 kg
- Dose
- Not routinely recommended
- Frequency
- Use only if explicitly prescribed
- Tracking Notes
- Safety and efficacy in infants under 6 months or weighing under 5 kg have not been established.
- Body Weight
- 5-7 kg
- Dose
- 125 mcg (0.5 mL of 250 mcg/mL solution)
- Frequency
- Every 6 to 8 hours
- Tracking Notes
- Must be administered via nebulizer under close medical supervision.
- Body Weight
- 8-10 kg
- Dose
- 125 to 250 mcg (0.5 to 1 mL of 250 mcg/mL solution)
- Frequency
- Every 6 to 8 hours
- Tracking Notes
- May be diluted with preservative-free sterile normal saline to match nebulizer volume requirements.
- Body Weight
- 11-15 kg
- Dose
- 250 mcg (1 mL of 250 mcg/mL solution)
- Frequency
- Every 6 to 8 hours
- Tracking Notes
- Typically administered in combination with a short-acting beta-2 agonist during acute bronchospasm.
- Body Weight
- 16-20 kg
- Dose
- 250 mcg (1 mL of 250 mcg/mL solution)
- Frequency
- Every 6 to 8 hours
- Tracking Notes
- In severe acute asthma, dosage may be repeated more frequently under direct emergency medical supervision.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routinely recommended | Use only if explicitly prescribed | Safety and efficacy in infants under 6 months or weighing under 5 kg have not been established. |
| 5-7 kg | 125 mcg (0.5 mL of 250 mcg/mL solution) | Every 6 to 8 hours | Must be administered via nebulizer under close medical supervision. |
| 8-10 kg | 125 to 250 mcg (0.5 to 1 mL of 250 mcg/mL solution) | Every 6 to 8 hours | May be diluted with preservative-free sterile normal saline to match nebulizer volume requirements. |
| 11-15 kg | 250 mcg (1 mL of 250 mcg/mL solution) | Every 6 to 8 hours | Typically administered in combination with a short-acting beta-2 agonist during acute bronchospasm. |
| 16-20 kg | 250 mcg (1 mL of 250 mcg/mL solution) | Every 6 to 8 hours | In severe acute asthma, dosage may be repeated more frequently under direct emergency medical supervision. |
Formulation
Purpose
Used for the prevention and treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema, and as an add-on therapy in acute asthma exacerbations.
Generic Name
Ipratropium bromideScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.