Amlodipine Besylate
Amlodipine Besylate is a long-acting dihydropyridine calcium channel blocker. It works by relaxing the blood vessels, allowing blood to flow more easily, which lowers blood pressure and decreases the workload on the heart.
Dosage by Body Weight
The usual starting dose for adults is 5 mg once daily, which may be increased to a maximum of 10 mg once daily depending on patient response. For pediatric patients aged 6 to 17 years, the usual dose is 2.5 mg to 5 mg once daily. Always take this medication exactly as prescribed by your doctor.
- Body Weight
- Below 5 kg
- Dose
- Not established
- Frequency
- Consult pediatrician
- Tracking Notes
- Safety and effectiveness in pediatric patients weighing under 5 kg or under 6 years of age have not been established.
- Body Weight
- 5-7 kg
- Dose
- Not established
- Frequency
- Consult pediatrician
- Tracking Notes
- Only use under strict, specialized pediatric cardiovascular supervision.
- Body Weight
- 8-10 kg
- Dose
- Not established
- Frequency
- Consult pediatrician
- Tracking Notes
- Safety and efficacy are not established for routine pediatric use in this weight range.
- Body Weight
- 11-15 kg
- Dose
- 0.05 to 0.2 mg/kg
- Frequency
- Once daily
- Tracking Notes
- Off-label dosing for pediatric hypertension typically starts at 0.05 to 0.1 mg/kg/day, titrated up to a maximum of 0.2 mg/kg/day (not exceeding 5 mg/day). Requires specialized liquid formulation.
- Body Weight
- 16-20 kg
- Dose
- 0.05 to 0.2 mg/kg
- Frequency
- Once daily
- Tracking Notes
- Off-label pediatric dosing ranges from 0.05 to 0.2 mg/kg/day up to a maximum of 5 mg/day. Must be individualized and monitored by a physician.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not established | Consult pediatrician | Safety and effectiveness in pediatric patients weighing under 5 kg or under 6 years of age have not been established. |
| 5-7 kg | Not established | Consult pediatrician | Only use under strict, specialized pediatric cardiovascular supervision. |
| 8-10 kg | Not established | Consult pediatrician | Safety and efficacy are not established for routine pediatric use in this weight range. |
| 11-15 kg | 0.05 to 0.2 mg/kg | Once daily | Off-label dosing for pediatric hypertension typically starts at 0.05 to 0.1 mg/kg/day, titrated up to a maximum of 0.2 mg/kg/day (not exceeding 5 mg/day). Requires specialized liquid formulation. |
| 16-20 kg | 0.05 to 0.2 mg/kg | Once daily | Off-label pediatric dosing ranges from 0.05 to 0.2 mg/kg/day up to a maximum of 5 mg/day. Must be individualized and monitored by a physician. |
Formulation
Purpose
Used to treat high blood pressure (hypertension) to lower the risk of stroke and heart attack, and to treat chest pain (angina) or other conditions caused by coronary artery disease.
Generic Name
Amlodipine BesylateBranded Drug Names
Amlodipine Besylate is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.